Research from Freedman Lab Reveals Surprising Finding About Common Cause of Kidney Disease

January 5, 2023 | Categories: Core Faculty, Research | Tagged: , ,

A paper from the Freedman Lab, published this week in Nature Communications, reveals a surprising finding about the way cysts form in PKD organoids, a discovery that could have clinical implications. Read More

ISCRM Researchers Identify Gene With Dual Influence on Bone and Muscle Development

November 29, 2022 | Categories: Core Faculty, Research | Tagged: , , , , ,

Using zebrafish as a model, researchers from the Musculoskeletal Systems Biology Lab describe how wnt16 dually influences bone and muscle development and growth. Read More

Cascadia Corridor Research Symposium Comes to Seattle

October 10, 2022 | Categories: Announcements, Core Faculty, Research | Tagged:

The symposium will take place November 3-4 on the UW Medicine South Lake Union campus and will feature keynote addresses from ISCRM Associate Director Jen Davis, PhD and David Granville, PhD, Professor and Associate Dean Research, Faculty of Medicine, University of British Columbia. Read More

MSBL Receives NIH Grant to Expand DEIA Mentorship

October 4, 2022 | Categories: Award, Core Faculty, Research | Tagged: , ,

The Musculoskeletal Systems Biology Lab (MSBL), directed by ISCRM faculty member Ron Kwon, has received a $431,765 award from the NIH in recognition of excellence in DEIA (diversity, equity, inclusion, and accessibility) mentorship. Read More

Xray image of a Zebrafish Fin

Exploring Regenerative Potential in Zebrafish and Humans

September 27, 2022 | Categories: Core Faculty, Research | Tagged: , , ,

A study from the Musculoskeletal Systems Biology Lab sheds a light on the characteristics of zebrafish cells that are able to differentiate from progenitor cells into bone cells, and then revert back to a progenitor state. Read More

Modeling a Muscle Disease in 3D

August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , ,

A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More

Group of people standing outside

Meet the 2022-2023 ISCRM Fellows

August 1, 2022 | Categories: Award, Research, Uncategorized | Tagged: , ,

State-funded ISCRM Fellowships enable students at the undergraduate, graduate, and postdoctoral level to advance research efforts aimed at addressing the root causes of diseases. Read More

Faculty headshot of Thelma Escobar, PhD

Grant for Escobar Lab Funds AML Research

July 13, 2022 | Categories: Award, Core Faculty, Research | Tagged: , , , , ,

Thelma Escobar, PhD is collaborating with the Doulatov Lab and the Stem Cell Core to study how mutations in the gene NPM1 drive AML onset. Read More

Faculty headshot of Patrick M. Boyle, PhD, PEng, FHRS

Boyle Lab Leads Effort to Improve Stroke Risk Assessment

July 5, 2022 | Categories: Award, Core Faculty, Research | Tagged: ,

ISCRM faculty member Patrick Boyle has received a five-year, $2.9 million grant from the National Heart, Lung, and Blood Institute to improve outcomes for stroke patients by identifying and testing individualized strategies for diagnosing and treating strokes. Read More

Primary cilia (red) lining the surface of human kidney organoids (gray).

Freedman Lab Explores the Role Cilia Play in Signaling, Cell Fate, and Disease Development

April 27, 2022 | Categories: Research | Tagged: , , , , , ,

In the Freedman Lab, knocking out primary cilia reveals insights about the role the organelles play in cell fate and disease development. Read More