Aided by Stem Cells, ISCRM Researchers Identify a Suspect in the Case of Infertility

February 7, 2019 | Categories: Core Faculty, Research | Tagged: ,

February 7, 2019 Of all the mysteries surrounding the beginning of human life, one question has drawn particular interest from researchers at the Institute for Stem Cell and Regenerative Medicine (ISCRM). Simply put, for women who are unable to get pregnant, what is happening at the cellular level that is preventing life from taking hold? […] Read More

ISCRM Labs Collaborate to Grow Heart Tissue In Vitro

February 4, 2019 | Categories: Research | Tagged: , , ,

February 4, 2019 Heart failure is the leading cause of death in the world. In the United States alone, hundreds of thousands of people succumb to the disease every year, while the costs of care and lost productivity drain more than $200 billion from the economy. Recent breakthroughs in stem cell research offer hope for […] Read More

Gene Therapy Cassettes Improved for Muscular Dystrophy

February 1, 2019 | Categories: Research | Tagged: , , ,

February 1, 2019 Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance.  The cassettes, which carry the therapy into muscle cells, contain newer versions of a miniaturized treatment gene. The micro-dystrophin, as the treatment gene is called, has been restructured to enhance its functionality. The revamped versions were developed […] Read More

Tietze Young Scientist Awards for Two ISCRM Faculty Members

January 31, 2019 | Categories: Award, Research

Two ISCRM faculty members, Dr. Smita Yadav, Assistant Professor, Pharmacology and Dr. Ronald Kwon, Associate Professor, Orthopedics and Sports Medicine, have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Using Stem Cells to Study the Causes of Autism Spectrum Disorder Autism Spectrum Disorder […] Read More

Enhancing the Development of Heart Cells Using Materials Derived From Silk

December 17, 2018 | Categories: Announcements, Core Faculty, Heart Regeneration, Research

In an exciting breakthrough that may have implications for stem cell-based treatment of heart disease, the lab of Dr. Deok-Ho Kim at the Institute for Stem Cell and Regenerative Medicine (ISCRM) has successfully used silk-based materials to enhance the development of stem-cell derived cardiomyocytes. In a recent study detailed in the Journal of Materials Chemistry, […] Read More

Potential Seen for Tailoring Acute Myeloid Leukemia Treatment

December 3, 2018 | Categories: Announcements, Research | Tagged: , ,

Drug response screening of leukemia stem cells offers clues to relapse and suggests ways to improve patient-specific therapies Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML). Research on the drug responses of leukemia stem cells may reveal why some […] Read More

ISCRM Faculty Shine a New Light on Scarring

October 12, 2018 | Categories: Research | Tagged: , , ,

Collaboration is the engine of scientific progress at UW Medicine and at the Institute of Stem Cell & Regenerative Medicine (ISCRM), where 130 researchers are developing stem cell-based approaches to treat diseases affecting nearly every organ and system in the human body.   Read More

UW Medicine Researchers Explore New Approaches to Treating Childhood Leukemia

October 1, 2018 | Categories: Research | Tagged: ,

Acute lymphocytic leukemia (ALL) is the most common type of childhood cancer, representing approximately 25% of cancer diagnoses in children 0-15. More than 3,000 new cases of ALL are diagnosed every year in the United States - and the incidence rate is rising. Read More

Researchers use stem cells to restore heart function in primates

July 2, 2018 | Categories: Research | Tagged: , ,

Results of a study published today in Nature Biotechnology suggest techniques that could treat patients with heart failure. Researchers at UW Medicine in Seattle have successfully used human stem cells to restore heart function in monkeys with heart failure. The findings suggest that the technique will be effective in patients with heart failure, the leading cause of death in the world. Read More

Understanding Alzheimers

May 23, 2018 | Categories: Research | Tagged: , , ,

New cell lines will allow researchers to probe the basic biology of Alzheimer’s. Currently, however, there are no treatments that can prevent or slow the progression of this memory-robbing disease, which affects more than 5 million Americans. One reason for this is that we really don’t know the cause of Alzheimer’s: It is known that brain cells that are crucial to forming new memories die. But we don’t know why. Read More