Insights on Genetic Causes of SIDS-linked Disease Published in Nature Communications

October 14, 2019 | Categories: Research | Tagged: , ,

Each year, according to the CDC, approximately 3,600 infant deaths in the United States are attributed to Sudden Unexplained Infant Death Syndrome (SUIDS) – an umbrella category that includes Sudden Infant Death Syndrome (SIDS). Read More

With NIH Funding, Freedman Lab to Use Kidney Organoids to Predict Adverse Effects of Genome Editing

October 1, 2019 | Categories: Announcements, Award, Research | Tagged: , , , ,

Nearly 40 million Americans are impacted by chronic kidney disease, a family of progressive conditions associated with widespread health complications, including higher risk for heart disease. Read More

Improved Method for Converting Stem Cells into Pancreatic Islet Progenitor Cells Detailed in iScience

August 29, 2019 | Categories: Announcements, Core Faculty, Research | Tagged: , , , , ,

Type 1 diabetes is a disease that occurs when the immune system attacks and kills the cells that produce insulin in the pancreas, known as beta-cells. Read More

ISCRM Researchers Discover “Missing Piece” of the Heart Regeneration Puzzle

August 21, 2019 | Categories: Announcements, Research | Tagged: , , , ,

Nearly 18 million people die each year from heart disease, making it the leading cause of death in the world. In the United States alone, the annual economic impact of heart disease exceeds $200 billion, a figure that is expected to rise dramatically. Read More

Research from Doulatov Lab in the Journal Blood Offers Stem Cell-Aided Insights on MDS Onset

June 13, 2019 | Categories: Research | Tagged: , ,

Myelodysplastic syndromes (MDS) are heterogenous blood disorders that affect up to 170,000 people in the United States, primarily over the age of 60. While early symptoms, including anemia (characterized by fatigue), are not serious, MDS is a high-risk factor for leukemia. Currently there are few treatment for MDS and the causes remain poorly understood. Read More

New Findings About dATP-Enhanced Heart Contractions Published in PNAS

May 21, 2019 | Categories: Core Faculty, Research | Tagged: , , , , ,

Heart failure is a widespread chronic condition that directly impacts nearly six million Americans, contributes to almost one in ten deaths in the United States, and drains an estimated $30 billion annually from our national economy. Read More

Breakthroughs in 3D Organ Printing Detailed in Science

May 2, 2019 | Categories: Core Faculty, Research | Tagged: , , ,

Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The new innovation allows scientists to create exquisitely entangled vascular networks that mimic the body's natural passageways for blood, air, lymph and other vital fluids. Read More

Studying Cell Signaling in the Prostate

April 15, 2019 | Categories: Core Faculty, Research | Tagged: , , ,

While prostate cancer may not be as deadly as other cancers – five-year survival rates can exceed 90%, especially if the disease is localized – incidence rates overall are increasing. For 2019 alone, The American Cancer Society predicts the United States will see roughly 175,000 new cases and 32,000 deaths associated with prostate cancer. Read More

ISCRM and the UW School of Dentistry Reveal Important New Findings About the Nature of Stem Cells in Human Teeth

February 22, 2019 | Categories: Research | Tagged: , , ,

Long before Hannele Ruohola-Baker became a leading stem cell researcher, she was a young hockey player skating on the frozen ponds of her native Finland. When she was ten years old, she lost a tooth to an errant puck. “I’d say that’s when my interest in regenerating teeth began,” says Dr. Ruohola-Baker, now a Professor of Biochemistry and Associate Director of the UW Medicine Institute for Stem Cell and Regenerative Medicine (ISCRM). Read More

Aided by Stem Cells, ISCRM Researchers Identify a Suspect in the Case of Infertility

February 7, 2019 | Categories: Core Faculty, Research | Tagged: ,

February 7, 2019 Of all the mysteries surrounding the beginning of human life, one question has drawn particular interest from researchers at the Institute for Stem Cell and Regenerative Medicine (ISCRM). Simply put, for women who are unable to get pregnant, what is happening at the cellular level that is preventing life from taking hold? […] Read More