Glia cells and neurons in the retina

Scientists regenerate retinal cells in mice

July 26, 2017 | Categories: Research | Tagged: , , , ,

Scientists have successfully regenerated cells in the retina of adult mice at the University of Washington School of Medicine in Seattle. Their results raise the hope that someday it may be possible to repair retinas damaged by trauma, glaucoma and other eye diseases. Their efforts are part of the UW Medicine Institute for Stem Cell […] Read More

Gene replacement therapy that works in dogs to be tested in children

May 18, 2017 | Categories: Research | Tagged: , , , ,

SEATTLE – KIRO 7 has learned of a revolutionary treatment, here in Seattle, that has saved the lives of dogs and is just months away from being tested in children. In video obtained by KIRO 7, dogs that were destined to die show no signs of the disease after a single infusion of gene-replacement therapy.  The […] Read More

Pioneering work on stem-cell therapies at UW deserves state support

April 9, 2017 | Categories: Research | Tagged: , , , , ,

IF you have a heart attack, hopefully you’ll survive. But your body will be forever changed. The world’s best doctors can’t undo the damage; instead, drugs and devices will help you live with a heart whose function too often dwindles. The body cannot replace muscle cells that die in heart attacks — maladies that help […] Read More

Transfer of the MTM1 gene into the weakened muscle tissue of dogs affected by myotubular myopathy restores muscle strength. The disease arises from a genetic mutation that disrupts the production of a protein needed for muscle function.

Gene therapy treats muscle-wasting disease in dogs

February 15, 2017 | Categories: Research | Tagged: , , ,

Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease. UW Medicine Institute for Stem Cell and Regenerative Medicine scientists are leading the multi-institutional research effort. The disease arises from a mutation in genes that normally make a protein, called myotubularin, […] Read More

New neurons (green) regenerated from Muller glia in two-week old mice.

Restoring sight: Can the retina be regenerated?

August 30, 2016 | Categories: Research | Tagged: , , ,

July 26, 2017 A UW Medicine lab sees a future where lost retinal cells might be revived Break a bone, it will heal. Fry a retinal cell? It’s gone forever. That’s why your mom told you never to stare at the sun. Vision starts in the retina, the part of the eye that translates light […] Read More

Rotational modeling process used in research to develop a rehealing glove.

UW Medicine researchers seek a way to regenerate digits

August 12, 2016 | Categories: Research | Tagged: , , ,

UW Medicine researchers seek a way to regenerate digits A 7-year-old girl sticks her finger through the spinning spokes of her brother’s bike. The tip gets torn off. She soon arrives in the emergency room, where Dr. Christopher Allan and his fellow UW Medicine surgeons face a decision. Should they attempt microsurgical reattachment? Suture the […] Read More

Xuan Guan

Disease-in-a-dish model to improve treatments

August 4, 2016 | Categories: Research | Tagged: , , ,

Scientists’ ability to guide cell growth drives one vision of healthcare’s future Say you’re sick. You head to your doctor and discuss personal details about your body. The doc thoughtfully checks your symptoms, maybe administers a test or two, and then delivers a diagnosis. When it’s time to recommend treatment, though, “personal” probably will yield […] Read More

Intestinal organoid

With CRISPR, Modeling Disease in Mini Organs

May 6, 2016 | Categories: Research | Tagged: , , , ,

Traditionally, gene therapy efforts have attempted to treat genetic diseases by modifying DNA inside a patient’s body, but it has been a challenge to deliver the genetic material to all the target tissue, let alone to do so safely. But in recent years, advances in gene editing and stem cell research have enabled scientists to […] Read More

Deepkiran Singh

Stem cell research gets undergrads out of classroom

March 23, 2016 | Categories: Research | Tagged: , ,

Students help conduct intensive, real-world research at UW Medicine lab UW undergraduate Randy Lu grasps a pair of tweezers in each hand. His fingers make imperceptible movements as he dissects the tiny abdomen of a fruit fly. The tweezers and Lu’s hands look garishly large next to the insect, which is a mere speck in […] Read More

Illustration of approach to ITOMIC study of cancer patients.

Study tells of cancer patient’s unprecedented level of care

January 25, 2016 | Categories: Research | Tagged: , , ,

32 researchers at 14 institutions joined to identify personalized treatment options for woman with metastatic triple-negative breast cancer A new report documents one cancer patient’s experience with an unprecedented level of individualized care, provided through the University of Washington Center for Cancer Innovation. In the study, 32 experts from 14 institutions teamed to identify potential interventions for a patient […] Read More