Previously Unappreciated Function of αE-catenin Uncovered by Cirulli and Crisa Labs
August 8, 2017 | Categories: Core Faculty, Research |
Crisa Lab Uncovers Novel Function of a Subset of Macrophages that Foster Pancreatic Islet Cell Growth
August 3, 2017 | Categories: Core Faculty, Research, Uncategorized |
Scientists regenerate retinal cells in mice
July 26, 2017 | Categories: Research |Scientists have successfully regenerated cells in the retina of adult mice at the University of Washington School of Medicine in Seattle. Their results raise the hope that someday it may be possible to repair retinas damaged by trauma, glaucoma and other eye diseases. Their efforts are part of the UW Medicine Institute for Stem Cell […] Read More
Gene replacement therapy that works in dogs to be tested in children
May 18, 2017 | Categories: Research |SEATTLE – KIRO 7 has learned of a revolutionary treatment, here in Seattle, that has saved the lives of dogs and is just months away from being tested in children. In video obtained by KIRO 7, dogs that were destined to die show no signs of the disease after a single infusion of gene-replacement therapy. The […] Read More
Pioneering work on stem-cell therapies at UW deserves state support
April 9, 2017 | Categories: Research |IF you have a heart attack, hopefully you’ll survive. But your body will be forever changed. The world’s best doctors can’t undo the damage; instead, drugs and devices will help you live with a heart whose function too often dwindles. The body cannot replace muscle cells that die in heart attacks — maladies that help […] Read More
Gene therapy treats muscle-wasting disease in dogs
February 15, 2017 | Categories: Research |Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease. UW Medicine Institute for Stem Cell and Regenerative Medicine scientists are leading the multi-institutional research effort. The disease arises from a mutation in genes that normally make a protein, called myotubularin, […] Read More
Restoring sight: Can the retina be regenerated?
August 30, 2016 | Categories: Research |July 26, 2017 A UW Medicine lab sees a future where lost retinal cells might be revived Break a bone, it will heal. Fry a retinal cell? It’s gone forever. That’s why your mom told you never to stare at the sun. Vision starts in the retina, the part of the eye that translates light […] Read More
UW Medicine researchers seek a way to regenerate digits
August 12, 2016 | Categories: Research |UW Medicine researchers seek a way to regenerate digits A 7-year-old girl sticks her finger through the spinning spokes of her brother’s bike. The tip gets torn off. She soon arrives in the emergency room, where Dr. Christopher Allan and his fellow UW Medicine surgeons face a decision. Should they attempt microsurgical reattachment? Suture the […] Read More
Disease-in-a-dish model to improve treatments
August 4, 2016 | Categories: Research |Scientists’ ability to guide cell growth drives one vision of healthcare’s future Say you’re sick. You head to your doctor and discuss personal details about your body. The doc thoughtfully checks your symptoms, maybe administers a test or two, and then delivers a diagnosis. When it’s time to recommend treatment, though, “personal” probably will yield […] Read More
With CRISPR, Modeling Disease in Mini Organs
May 6, 2016 | Categories: Research |Traditionally, gene therapy efforts have attempted to treat genetic diseases by modifying DNA inside a patient’s body, but it has been a challenge to deliver the genetic material to all the target tissue, let alone to do so safely. But in recent years, advances in gene editing and stem cell research have enabled scientists to […] Read More