Kavitha T. Kuppusamy led a study of a molecular switch that promotes heart cell maturation.

Molecular switch matures heart cells derived from stem cells

May 12, 2015 | Categories: Research | Tagged: , , ,

Discovery may prove a major advance in the development of stem cell treatments for heart disease A molecular switch that seems to be essential  for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered. The discovery should help scientist better understand how human hearts mature. Of particular interest to stem […] Read More

At a University of Washington stem cell research lab

Dying cells can protect their stem cells from destruction

May 11, 2015 | Categories: Research | Tagged: , ,

An SOS signal from dying daughter cells allows their mother stem cells to protect themselves from radiation and chemotherapy damage Cells dying as the result of radiation exposure or chemotherapy can send a warning to nearby stem cells. The chemical signal allows the stem cells to escape the same fate, University of Washington researchers report […] Read More

As the patients' damaged hearts were fitted with a ventricular-assist device

Injection of marrow stem cells into the heart is proven ineffective

April 21, 2015 | Categories: Research | Tagged: , ,

Marrow stem cells were injected into failing hearts of 6 patients awaiting transplantation A small study by University of Washington researchers has found no sign that bone-marrow stem-cell injections stimulated repair in the damaged hearts of patients awaiting transplantation. The results were published in the Journal of the American Academy of Cardiology. Dr. April Stempien-Otero, UW associate professor of […] Read More

Developing human embryos that could be used to harvest stem cells.

The Trials of Stem Cell Therapy

September 15, 2014 | Categories: Research | Tagged: ,

Stem cells broke into the public consciousness in the early 1990s, alluring for their potential to help the body beat back diseases of degeneration Alzheimer’s, and to grow new parts to treat conditions like spinal cord injuries. Progress has been slow. The Michael J. Fox Foundation for Parkinson’s Research, an early supporter of stem cell research, […] Read More

Dr. Chuck Murry

U.S. health research funding critical, NIH head tells UW meet

August 12, 2014 | Categories: Research | Tagged: , ,

In a whirlwind tour through UW Medicine’s research laboratories in South Lake Union, Dr. Francis Collins, director of the National Institutes of Health (NIH), swung easily through a show-and-tell that ranged from a dish full of lab-created beating human heart cells to a gene-deletion step in deciphering how immune systems respond to scary viruses such as […] Read More

The Heart of Stem Cell Research

August 4, 2014 | Categories: Research | Tagged: ,

ISCRM’s Drs. Chuck Murry, Michael Laflamme and April Stempien-Otero discuss stem cells and heart regeneration in the latest podcast at UW Medicine Pulse. Listen to the episode here. Read More

Dr. Michael Laflamme

Scientists regenerate heart muscle in primates

April 30, 2014 | Categories: Research | Tagged: , ,

Findings bring stem cell therapy for damaged hearts closer to clinical trials In a major advance, researchers at the University of Washington have successfully restored damaged heart muscle of monkeys using heart cells created from human embryonic stem cells. The results of the experiment appear in the April 30 advanced online edition of the journal Nature. The findings […] Read More

ISCRM Faculty Member, Dr. Phil Horner, Featured on UW|360

April 24, 2014 | Categories: Research | Tagged: ,

Phil Horner, PhD, Associate Professor of Neurological Surgery at the UW, is working on a unique approach to restoring limb function after chronic spinal cord injury. Dr. Horner and his colleagues are researching how stem cell therapy and stimulation can be used together to restore limb function for people suffering from paralysis after a spinal […] Read More

Julie Mathieu (left)

Proteins that control energy use necessary to form stem cells

March 21, 2014 | Categories: Research | Tagged: , , ,

Findings advance efforts to reprogram mature cells for organ repair Two proteins that control how cells break down glucose play a key role in forming human stem cells, University of Washington researchers have found. The finding has implications for future work in both regenerative medicine and cancer therapy. A report on this research appears online March 20 […] Read More

Dr. Carol Ware at work in her laboratory at the Institute for Stem Cell and Regenerative Medicine

New cell line should accelerate embryonic stem cell research

March 10, 2014 | Categories: Research | Tagged: , ,

These cells appear at the earliest stages of an embryo and can form all human cell types University of Washington researchers have created a line of human embryonic stem cells with the ability to develop into a far broader range of tissues than most existing cell lines. “These cells will allow us to gain a […] Read More