Deepkiran Singh

Stem cell research gets undergrads out of classroom

March 23, 2016 | Categories: Research | Tagged: , ,

Students help conduct intensive, real-world research at UW Medicine lab UW undergraduate Randy Lu grasps a pair of tweezers in each hand. His fingers make imperceptible movements as he dissects the tiny abdomen of a fruit fly. The tweezers and Lu’s hands look garishly large next to the insect, which is a mere speck in […] Read More

Illustration of approach to ITOMIC study of cancer patients.

Study tells of cancer patient’s unprecedented level of care

January 25, 2016 | Categories: Research | Tagged: , , ,

32 researchers at 14 institutions joined to identify personalized treatment options for woman with metastatic triple-negative breast cancer A new report documents one cancer patient’s experience with an unprecedented level of individualized care, provided through the University of Washington Center for Cancer Innovation. In the study, 32 experts from 14 institutions teamed to identify potential interventions for a patient […] Read More

Drs. Ruohola-Baker

Changes in metabolites can regulate earliest stages of development

November 16, 2015 | Categories: Research | Tagged: , , ,

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells. The recent findings, discovered by members of the Ruohola-Baker Lab, should improve scientists’ ability to use embryonic stem cells to grow new tissues and organs to replace […] Read More

A mini-kidneyorganoid of 1 mm diameter grown from a patient's stem cells.

Mini-kidney organoids re-create disease in lab dishes

October 23, 2015 | Categories: Research | Tagged: , , , ,

Stem-cell biology and gene editing advances offer hope for kidney regeneration, drug discovery Mini-kidney organoids that re-create human kidney disease have now been grown in laboratory petri dishes. The achievement, believed to be the first of its kind, resulted from combining stem cell biology with leading-edge gene-editing techniques.  The journal Nature Communications reports the findings […] Read More

Ntombi

Struggling to save black rhinos, scientists are crowdfunding to preserve their DNA

July 13, 2015 | Categories: Research | Tagged: , , , ,

Ntombi is a six-year-old black rhino from South Africa, one of around 5,000 black rhinos left in the wild. She’s also the starting point for what a team of scientists hope to be a “bio-bank” of genetic information that could be used to save the species. ISCRM’s Interim Director, Chuck Murry, is a member of the team. Ntombi would […] Read More

Kavitha T. Kuppusamy led a study of a molecular switch that promotes heart cell maturation.

Molecular switch matures heart cells derived from stem cells

May 12, 2015 | Categories: Research | Tagged: , , ,

Discovery may prove a major advance in the development of stem cell treatments for heart disease A molecular switch that seems to be essential  for embryonic heart cells to grow into more mature, adult-like heart cells has been discovered. The discovery should help scientist better understand how human hearts mature. Of particular interest to stem […] Read More

At a University of Washington stem cell research lab

Dying cells can protect their stem cells from destruction

May 11, 2015 | Categories: Research | Tagged: , ,

An SOS signal from dying daughter cells allows their mother stem cells to protect themselves from radiation and chemotherapy damage Cells dying as the result of radiation exposure or chemotherapy can send a warning to nearby stem cells. The chemical signal allows the stem cells to escape the same fate, University of Washington researchers report […] Read More

As the patients' damaged hearts were fitted with a ventricular-assist device

Injection of marrow stem cells into the heart is proven ineffective

April 21, 2015 | Categories: Research | Tagged: , ,

Marrow stem cells were injected into failing hearts of 6 patients awaiting transplantation A small study by University of Washington researchers has found no sign that bone-marrow stem-cell injections stimulated repair in the damaged hearts of patients awaiting transplantation. The results were published in the Journal of the American Academy of Cardiology. Dr. April Stempien-Otero, UW associate professor of […] Read More

Developing human embryos that could be used to harvest stem cells.

The Trials of Stem Cell Therapy

September 15, 2014 | Categories: Research | Tagged: ,

Stem cells broke into the public consciousness in the early 1990s, alluring for their potential to help the body beat back diseases of degeneration Alzheimer’s, and to grow new parts to treat conditions like spinal cord injuries. Progress has been slow. The Michael J. Fox Foundation for Parkinson’s Research, an early supporter of stem cell research, […] Read More

Dr. Chuck Murry

U.S. health research funding critical, NIH head tells UW meet

August 12, 2014 | Categories: Research | Tagged: , ,

In a whirlwind tour through UW Medicine’s research laboratories in South Lake Union, Dr. Francis Collins, director of the National Institutes of Health (NIH), swung easily through a show-and-tell that ranged from a dish full of lab-created beating human heart cells to a gene-deletion step in deciphering how immune systems respond to scary viruses such as […] Read More