Dr. Daniel Miller studies the molecular basis of muscle disorders in his lab at UW Medicine South Lake Union.

Mutations in genes that modify DNA packaging result in form of muscular dystrophy

November 19, 2012 | Categories: Research | Tagged: , , ,

November 19, 2012 A recent finding by medical geneticists sheds new light on how facioscapulohumeral muscular dystrophy develops and how it might be treated. More commonly known as FSHD, the devastating disease affects both men and women. FSHD is usually an inherited genetic disorder, yet sometimes appears spontaneously via new mutations in individuals with no […] Read More

Charles Sabine On Genetic Testing

November 8, 2012 | Categories: Research | Tagged: ,

Charles Sabine was a war correspondent with NBC for 25 years, covering conflicts all over the world — including Bosnia, Baghdad, and the Rwanda genocide. His reporting garnered him an Emmy and many other journalism awards. But four years ago his focus completely changed after getting a genetic test that revealed a lethal fate. Listen […] Read More

Dr. Michael Laflamme

UW researchers see work as step toward regenerating human heart

August 7, 2012 | Categories: Research | Tagged: , , ,

Two University of Washington scientists, using expertise in stem cells, cardiology, pathology, cell biology and the electrophysiology of the heart, are a step closer to their holy grail: regenerating a damaged heart. Human heart-muscle cells injected into the damaged heart of a guinea pig not only strengthened the heart’s ability to contract, the cells synchronized […] Read More

A colony of human embryonic stem cells.

Embryonic stem cells shift metabolism in a cancer-like way upon implanting in the uterus

March 23, 2012 | Categories: Research | Tagged: ,

March 23, 2012 Shortly after a mouse embryo starts to form, some of its stem cells undergo a dramatic metabolic shift to enter the next stage of development, Seattle researchers report today. These stem cells start using and producing energy like cancer cells. This discovery is published today in EMBO, the European Molecular Biology Organization journal. […] Read More

ISCRM's Director, Randy Moon, featured in The Scientist

November 1, 2010 | Categories: Research | Tagged: ,

Randall Moon has looked to tadpoles and stem cells for clues about embryonic development and cell fate. Now he has his eye on turning biology into therapy. It was one of those ‘eureka’ moments,” says Randy Moon of the experiment in which he first laid eyes on the awesome power of Wnt. Andrew McMahon of the Department […] Read More

A colony of human embryonic stem cells stained with fluorescent markers.

U.S. Circuit Court of Appeals temporarily lifts stem cell ban

September 9, 2010 | Categories: Research | Tagged: ,

In the Puget Sound Business Journal’s Sept. 6 print edition, I wrote about how the University of Washington is grappling with a recent court ruling that halted federal funding for human embryonic stem cell research (subscription required). The UW’s preliminary estimate was that it could lose $16 million in funding from the National Institutes of […] Read More

University of Washington stem cell research in limbo

September 5, 2010 | Categories: Research | Tagged: ,

The University of Washington could be hit hard by a recent court ruling that halted federal funding for human embryonic stem cell research. UW scientists stand to lose at least $16 million in funding from the National Institutes of Health over the next five to six years unless the court decision is reversed, according to […] Read More

This is Dr. Charles "Chuck" Murry

Major Improvements Made In Engineering Heart Repair Patches From Stem Cells

October 9, 2009 | Categories: Research | Tagged: , ,

University of Washington (UW) researchers, including Dr. Charles “Chuck” Murry, professor of pathology and bioengineering, have succeeded in engineering human tissue patches free of some problems that have stymied stem-cell repair for damaged hearts. The disk-shaped patches can be fabricated in sizes ranging from less than a millimeter to a half-inch in diameter. Until now, engineering tissue […] Read More

Drs. Randy Moon and Tony Blau

Seattle researchers applaud lifting of stem-cell restrictions

March 10, 2009 | Categories: Research | Tagged: , ,

Researchers in Seattle who work with embryonic stem cells reacted with scientific relief and personal jubilation to President Obama’s decision Monday to reverse Bush-era restrictions that have hobbled their field for much of this decade. At the University of Washington, which has one of the nation’s largest concentration of researchers studying cells from human embryos, […] Read More