ISCRM Researchers Recover Cells from Hydrogels with Minimal Disturbance
March 1, 2023 | Categories: UncategorizedResearch from the DeForest and Davis Labs describes a new method for cell extraction using engineered versions of an enzyme called sortase that have evolved to recognize and break specific peptide sequences. Read More
Science Nights at the Collective
February 21, 2023 | Categories: UncategorizedJoin ISCRM at the Collective in South Lake Union on the evening of February 28 for Frog Envy and Fingertips: The Science of Regeneration, a free public science talk. Read More
Ganglion cells created in mice in bid to fix diseased eyes
December 13, 2022 | Categories: UncategorizedA UW Medicine team led by Tom Reh, PhD had previously shown that neurons could be coaxed from glial cells in the retinal tissue of mice. Now they’ve refined the process to produce specific cells. Read More
Another Job for Mighty Mitochondria: Regulating Stem Cell Division
December 8, 2022 | Categories: UncategorizedResearch from the Ruohola-Baker Lab shows that mitochondria determine whether a stem cell can reproduce or not, a finding that sheds new light on the factors that influence cell cycles. Read More
Special Issue in Frontiers in Cell and Developmental Biology Edited by David Mack, Mark Bothwell, and Alec Smith
October 14, 2022 | Categories: UncategorizedDavid Mack, Mark Bothwell, and Alec Smith are the editors of a special issue of Frontiers in Cell & Developmental Biology that explores different models for investigating neuromuscular disease and weighing the pros and cons of stem cell-based models versus cell lines and animal models. Read More
Modeling a Muscle Disease in 3D
August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized |A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More
Meet the 2022-2023 ISCRM Fellows
August 1, 2022 | Categories: Award, Research, Uncategorized |State-funded ISCRM Fellowships enable students at the undergraduate, graduate, and postdoctoral level to advance research efforts aimed at addressing the root causes of diseases. Read More
Deletion of Lamin B1 Linked to Nuclear Abnormalities Seen in Cancer
March 11, 2022 | Categories: Research, Uncategorized |Using gene-editing tools to decrease expression of lamin B1 in two stem cell models, the researchers show that deletion of lamin B1 causes change in stem cell function and nuclear shape – and contributes to leukemia progression. Read More
ISCRM Research Sheds New Light on COVID-19 and Kidney Health
December 2, 2021 | Categories: Core Faculty, Research, Uncategorized |ISCRM researchers use kidney organoids to demonstrate that COVID-19 is capable of infecting kidney cells directly and test whether a synthetic protein designed by the Institute for Protein Design (IPD) might be capable of preventing infection. Read More
Meet the 2021-2022 ISCRM Fellows
September 14, 2021 | Categories: UncategorizedThe 2021-2022 ISCRM Fellows were selected from a deep pool of undergraduate students, PhD students, and postdoc. Each ISCRM Fellow has received a state-funded fellowship to support their research. Read More