Deletion of Lamin B1 Linked to Nuclear Abnormalities Seen in Cancer

March 11, 2022 | Categories: Research, Uncategorized | Tagged: , ,

Using gene-editing tools to decrease expression of lamin B1 in two stem cell models, the researchers show that deletion of lamin B1 causes change in stem cell function and nuclear shape – and contributes to leukemia progression. Read More

Green and purple stained organoid

ISCRM Research Sheds New Light on COVID-19 and Kidney Health

December 2, 2021 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

ISCRM researchers use kidney organoids to demonstrate that COVID-19 is capable of infecting kidney cells directly and test whether a synthetic protein designed by the Institute for Protein Design (IPD) might be capable of preventing infection. Read More

grid of four young scientists

Meet the 2021-2022 ISCRM Fellows

September 14, 2021 | Categories: Uncategorized

The 2021-2022 ISCRM Fellows were selected from a deep pool of undergraduate students, PhD students, and postdoc. Each ISCRM Fellow has received a state-funded fellowship to support their research. Read More

Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration

June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized | Tagged: , , ,

New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More

ISCRM Welcomes Thelma Escobar

May 6, 2021 | Categories: Uncategorized

Thelma Escobar, PhD, joins the University of Washington as an Assistant Professor of Biochemistry and an ISCRM faculty member Read More

Study Yields New Clue to Strokes of Undetermined Source

May 4, 2021 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

Simulations shed light on heart-scarring similarities among patients with atrial fibrillation and those who had embolic stroke but no atrial fibrillation. Read More

Rainbow Heart

ISCRM Researchers Use Rainbow Reporters to Examine Proliferation of Engrafted Heart Cells

April 19, 2021 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized | Tagged: , , , ,

ISCRM investigators use rainbow cell technology to demonstrate that injected heart cells proliferate, a finding that could help researchers enhance the efficacy of cell therapy for heart disease and other conditions. Read More

Supercharging Antibodies for Better Medicine

April 2, 2021 | Categories: Uncategorized | Tagged: , , , ,

Researchers from the Ruohola-Baker Lab have collaborated with the Institute for Protein Design on a technology in which designed proteins assemble antibodies in nanocage structures, increasing their potency against cancer, COVID-19, and other diseases. Read More

Fighting Racial Inequity by Funding Black Scientists

January 26, 2021 | Categories: Uncategorized

More than 260 women faculty in biomedical engineering call on NIH to address funding disparities that discriminate against Black scientists Read More