Young Lab Links Loss of SORL1 Gene to Increased Alzheimer’s Risk

June 2, 2020 | Categories: Research | Tagged: , , ,

To overcome the inherent challenges in studying the brain, one ISCRM team used stem cell technology to implicate a gene known as SORL1 in some types of Alzheimer’s and to shed new light on why many promising treatments for this disease have hit dead ends in clinical trials. Read More

Understanding Alzheimers

May 23, 2018 | Categories: Research | Tagged: , , ,

New cell lines will allow researchers to probe the basic biology of Alzheimer’s. Currently, however, there are no treatments that can prevent or slow the progression of this memory-robbing disease, which affects more than 5 million Americans. One reason for this is that we really don’t know the cause of Alzheimer’s: It is known that brain cells that are crucial to forming new memories die. But we don’t know why. Read More

Stem-cell study points to new approach to Alzheimer’s disease

March 1, 2018 | Categories: Research | Tagged: ,

Improving the trafficking of cellular proteins in brain cells holds possibilities for new treatments and even prevention for Alzheimer’s disease, results of a new study suggest. Researchers found that a compound that enhances the shuttling of proteins within cells reduced the production of forerunners of two proteins implicated in brain cell death. Read More