Julie Mathieu (left)

Proteins that control energy use necessary to form stem cells

March 21, 2014 | Categories: Research | Tagged: , , ,

Findings advance efforts to reprogram mature cells for organ repair Two proteins that control how cells break down glucose play a key role in forming human stem cells, University of Washington researchers have found. The finding has implications for future work in both regenerative medicine and cancer therapy. A report on this research appears online March 20 […] Read More

"The contribution of the women enrolling in this trial is invaluable and their decision to participate

Study’s ‘panomic’ approach to advanced breast cancer

March 3, 2014 | Categories: Research | Tagged: , , ,

Trial enrollees sought; effort involves sharing tumors’ responses to therapy in massive public online database. Ten women with advanced breast cancer will participate in one of the most intensive clinical trials ever conducted to identify molecular changes in individual tumors and to understand the strategies cancers adopt to escape chemotherapy. The study is seeking enrollees. University of […] Read More

UW researchers developing patch for damaged hearts

February 14, 2014 | Categories: Research | Tagged: ,

Five million Americans are living with heart disease, heart failure and 715,000 will have a heart attack this year. Now researchers at the University of Washington are working on a new way to repair damaged hearts with a biological band-aid. Read More

Childers displays a dog family tree showing those affected and unaffected by an inherited muscle disorder similar to X-linked myotubular myopathy in people.

Gene therapy leads to robust improvements in animal model of fatal muscle disease

January 22, 2014 | Categories: Research | Tagged: , ,

January 22, 2014 Preclinical studies show that gene therapy can improve muscle strength in small- and large-animal models of a fatal congenital childhood disease know as X-linked myotubular myopathy. The findings, appearing  as the cover story in the January 22, 2014 issue of Science Translational Medicine, also demonstrate the feasibility of future clinical trials of gene therapy for […] Read More

Dr. Charles Murry in his heart muscle cell research lab.

Dr. Chuck Murry elected as American Association for the Advancement of Science fellow

November 26, 2013 | Categories: Announcements | Tagged: ,

Five University of Washington researchers are among 388 new fellows of the American Association for the Advancement of Science. Election as a fellow of AAAS is an honor bestowed upon members by their peers. Fellows are recognized for meritorious efforts to advance science or its applications. Read the full story at UW Today. Read More

2013 UW recipients

ISCRM's Dr. Ying Zheng honored by NIH for innovative biomedical research

September 30, 2013 | Categories: Announcements | Tagged: , , , , ,

The National Institutes of Health has awarded nearly 80 grants to scientists working in biomedical research as part of this year’s High Risk-High Reward program. Three University of Washington faculty members are among those honored with a grant. The research program encourages scientists to pursue creative and innovative ideas about biomedical and behavioral research with the aim […] Read More

Stained bone marrow aspirate from a patient with acute lymphoblastic leukemia.

Gene for most common childhood cancer identified

September 9, 2013 | Categories: Research | Tagged: , ,

September 9, 2013 An aberrant gene has been found to cause the most common childhood cancer in the world, pre-B cell acute lymphoblastic leukemia. The gene, PAX5, has long been known to be involved in acute lymphoblastic leukemia.  The new study indicates a mutation in the gene alone is sufficient to eventually cause the disease, […] Read More

Drs. Randall Moon and Jason Berndt in March 22 edition of Science

May 10, 2013 | Categories: Announcements | Tagged: , , ,

Randall Moon, director of the UW’s Institute for Stem Cell & Regenerative Medicine (ISCRM) and professor of pharmacology, and Jason Berndt, acting instructor of pharmacology, wrote a review in the March 22 edition of Science about the promise of manipulating Wnt pathways for disease treatment. Read the full story at UW Medicine Online News. Read More

American Academy of Arts and Sciences selects Dr. Randall Moon as Fellow

April 29, 2013 | Categories: Announcements | Tagged: , , , ,

University of Washington faculty members Susan Eggers and Randall Moon have been elected fellows of the American Academy of Arts and Sciences. The 4,000 fellows and 600 foreign honorary members of the academy include more than 250 Nobel Prize laureates and 60 Pulitzer Prize winners. Read the full story at UW Today. Read More

Gene variants that affect brain signal receptors may be one of several causes of schizophrenia symptoms

Brain cell signal network genes linked to schizophrenia risk in families

April 3, 2013 | Categories: Research | Tagged: , ,

May 14, 2013 New genetic factors that predispose to schizophrenia have been uncovered in five families with several affected relatives. The psychiatric disorder can disrupt thinking, feeling, and acting, and blur the border between reality and imagination. Dr. Debby W. Tsuang, professor of psychiatry and behavioral sciences, and Dr. Marshall S. Horwitz, professor of pathology, […] Read More