Freedman Lab Explores the Role Cilia Play in Signaling, Cell Fate, and Disease Development
April 27, 2022 | Categories: Research |In the Freedman Lab, knocking out primary cilia reveals insights about the role the organelles play in cell fate and disease development. Read More
Nudging Cells to Repair Damaged Retinas
October 25, 2021 | Categories: Core Faculty, Research |Researchers led by ISCRM faculty member Tom Reh induce support cells in the retina to become neurons, an approach that someday could help restore vision. Read More
Color-Coding Technology Reveals New Insights About Stem Cell Biology
July 29, 2020 | Categories: Research |Several years ago, Danny El-Nachef was given a mission to create a tool to observe and track how stem cells behaved during the earliest stages of human heart development. While the focus of the challenge was human biology, the x-factor in the solution came from the sea. Read More
Improved Method for Converting Stem Cells into Pancreatic Islet Progenitor Cells Detailed in iScience
August 29, 2019 | Categories: Announcements, Core Faculty, Research |Type 1 diabetes is a disease that occurs when the immune system attacks and kills the cells that produce insulin in the pancreas, known as beta-cells. Read More
ISCRM Researchers Discover “Missing Piece” of the Heart Regeneration Puzzle
August 21, 2019 | Categories: Announcements, Research |Nearly 18 million people die each year from heart disease, making it the leading cause of death in the world. In the United States alone, the annual economic impact of heart disease exceeds $200 billion, a figure that is expected to rise dramatically. Read More
Move over Gucci; researchers create designer stem cells
September 1, 2017 | Categories: Research |UW Medicine researchers recently lead a successful effort to create “designer” stem cells that might lead to advances in cancer and aging, they say. In a paper published in the journal PNAS, the scientists showed for the first time that a computer-generated protein can be inserted into stem cells to change their epigenetic memory, whose role is to ensure that a cell’s DNA sequence remains intact as it divides. Read More
UW Medicine researchers seek a way to regenerate digits
August 12, 2016 | Categories: Research |UW Medicine researchers seek a way to regenerate digits A 7-year-old girl sticks her finger through the spinning spokes of her brother’s bike. The tip gets torn off. She soon arrives in the emergency room, where Dr. Christopher Allan and his fellow UW Medicine surgeons face a decision. Should they attempt microsurgical reattachment? Suture the […] Read More
Disease-in-a-dish model to improve treatments
August 4, 2016 | Categories: Research |Scientists’ ability to guide cell growth drives one vision of healthcare’s future Say you’re sick. You head to your doctor and discuss personal details about your body. The doc thoughtfully checks your symptoms, maybe administers a test or two, and then delivers a diagnosis. When it’s time to recommend treatment, though, “personal” probably will yield […] Read More