As an ISCRM REU Fellow, Birva Pinto will investigate the genetic mutation G159D in cardiac troponin C (cTnC) related to Dilated Cardiomyopathy (DCM), a disease that enlarges the heart chambers, […] Read More
Cystic Fibrosis (CF) is a life-limiting genetic disease caused by a mutation of CFTR, eventually leading to respiratory failure. With an ISCRM fellowship award, Jasime Villegas aims to create a CRISPR-Cas9 […] Read More
With ISCRM fellowship funding, Willow Chernoske will develop and conduct a proof of concept for a CRISPR-Cas12a biotinylation system designed by the Escobar Lab to determine the epigenetic mechanisms that […] Read More
To improve the field’s understanding of MBNL1-directed transcriptome maturation, Kalen Robeson will use human iPSC models to determine the role of MBNL1 in differentiation into skeletal muscle and to determine […] Read More
With her ISCRM fellowship, Brizzia Munoz Robles will develop a generalizable strategy to customize the biochemical properties of cell-laden biomaterials in 4D through functional protein photoassembly. The goal is to […] Read More
Funding will allow Ross Bretherton to explore the role of dilated cardiomyopathy and cardiac fibrosis in heart failure. In his investigation, Bretherton will characterize crosstalk between cardiomyocytes, cardiac fibroblasts, and […] Read More
Arafat Fasuyi will test her hypothesis that generating hardware and bioinks for a 3D bioprinting (SLATE) that can achieve higher resolution printing of microvasculature will enable the Stevens Lab to produce […] Read More
In the Cardiac Systems Simulation Lab, Jamie Yang is conducting a computational study to establish the feasibility of using optogenetic stimulation to suppress ventricular arrhythmias associated with human pluripotent stem […] Read More
As an ISCRM Undergraduate Fellow, Anika Ghelani will investigate the biomechanical role of the chaperone protein melusin in humans using engineered heart tissues (EHTs) created from wild-type hiPSC-CMs and hiPSC-CMs […] Read More
As an ISCRM Fellow, Elisa Clark will undertake a project aimed at improving efficacy of engineered T cell therapies against solid tumors using cytokine pre-treatment. Clark will test how cytokines […] Read More