With support from the ISCRM Fellowship, Theresa is developing two complementary high-throughput single-cell techniques to investigate disease-associated enhancers in retinal organoids. Enhancers—noncoding DNA elements that regulate gene expression—have been linked to […] Read More
Like other organs, the heart forms scar tissue in response to stress or injury. Cardiac fibroblasts are the cells in the heart responsible for regulating production and degradation of scar […] Read More
As an ISCRMU Fellow, Aleah will investigate the relationship between neurons and microglia. In their resting state, microglia support neuronal health and network formation; however, it remains unclear whether they […] Read More
Unlike non-mammalian vertebrates, hair cell damage in the mature mammalian cochlea leads to permanent hearing loss. There is great need for the discovery of new factors that promote hair cell […] Read More
With a goal of advancing regenerative medicine approaches to treating diabetes, ISCRM fellow Mark Andrade will explore the feasibility of activating Sonic Hedghog and/or Wnt signaling in pancreatic beta-cells “after” […] Read More
Using zebrafish as an in vivo model, ISCRM Fellow Erik Black will advance research efforts underway to better understand the mechanisms underlying the transition from stem cells to specialized cells […] Read More