My doctoral research investigates how a small RNA molecule, microRNA-192, guides human stem cells toward a pancreatic beta cell fate. Using a CRISPR-Cas9-engineered, inducible miRNA system, I aim to improve […] Read More
With support from the ISCRM fellowship, Sarah John aims to investigate how the dysfunction of TAOK1 kinase results in perturbed early brain development and macrocephaly. Sarah will utilize hiPSCs harboring […] Read More
As an ISCRM Fellow, Scott Schactler is characterizing the microenvironment of the lncRNA Xist during X-chromosome inactivation using photocatalyst-powered super-resolution proximity-labeling tools. Using Oligonucleotide-directed proximity-interactome MAPing (O-MAP) in a cell […] Read More