Akhila Bourampeta

Myotonic dystrophy (DM) is a genetic disease caused by CTG sequence repeat expansion in the DMPK gene, resulting in toxic RNAs that cause loss of function of MBNL1 protein and […] Read More

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Charlie Thel

 Like other organs, the heart forms scar tissue in response to stress or injury. Cardiac fibroblasts are the cells in the heart responsible for regulating production and degradation of scar […] Read More

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Rachelle Soriano

In the Davis and Regnier Labs, Rachelle Soriano is helping to characterize human beta myosin mutation E525K to determine its effects on sarcomere contraction and organization. The characterization of this […] Read More

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Joanna Agana

As a Bothell Fellow, Joanna Argana and a team of researchers from the Davis Lab examined the importance of external cues from the myocardium and extracellular environment in regulating how the […] Read More

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Kalen Robeson

To improve the field’s understanding of MBNL1-directed transcriptome maturation, Kalen Robeson will use human iPSC models to determine the role of MBNL1 in differentiation into skeletal muscle and to determine […] Read More

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Ross Bretherton

Funding will allow Ross Bretherton to explore the role of dilated cardiomyopathy and cardiac fibrosis in heart failure. In his investigation, Bretherton will characterize crosstalk between cardiomyocytes, cardiac fibroblasts, and […] Read More