Ramila Gulieva
Current human kidney organoid models, derived from pluripotent stem cells, face significant limitations. They remain structurally immature, functionally incomplete, and often highly variable between batches, lacking the vascularization and specialized […] Read More about Ramila Gulieva
Noah Jackson Bowers
As an ISCRMU fellow, Noah will research the potential of the use of electrophysiologic DNA gene editing in the creation of stem cell lines for improved cardiac remuscularizaton therapy. Specifically, […] Read More about Noah Jackson Bowers
Caleb Kono
Skeletal muscle has an extraordinary ability to regenerate, but this process declines sharply with age and disease, leading to weakness and frailty. A major challenge is that the genetic programs […] Read More about Caleb Kono
Divya Avnoor
Since their introduction in 2006, human iPSCs have enabled a generation of lineage-specific cell lines and organoids. However, bridging in vitro findings to whole-organism outcomes remains slow. Supported by an […] Read More about Divya Avnoor
Theresa Chen
With support from the ISCRM Fellowship, Theresa is developing two complementary high-throughput single-cell techniques to investigate disease-associated enhancers in retinal organoids. Enhancers—noncoding DNA elements that regulate gene expression—have been linked to […] Read More about Theresa Chen
Olivia Waters
As an ISCRM fellow, Olivia will investigate human placental cells’ tolerance to severe genomic stress. Compared to their parental human pluripotent stem cells (hPSCs), trophoblast stem cells (TSCs) and placentas […] Read More about Olivia Waters
Evelyn Abraham
As an ISCRM postdoctoral fellow, Evelyn Abraham will validate reprogramming of human Müller glia as a treatment for retinal degenerative diseases. She will use patient-derived retinal organoids to model late-stage […] Read More about Evelyn Abraham
Dorice Goune
Liver disease causes millions of deaths each year, yet scientists still lack the detailed structural information needed to 3D print a working liver. With support from ISCRM Fellowship, Dorice Goune […] Read More about Dorice Goune
Charlie Thel
Like other organs, the heart forms scar tissue in response to stress or injury. Cardiac fibroblasts are the cells in the heart responsible for regulating production and degradation of scar […] Read More about Charlie Thel
Lei Gao
Our nervous system is wired with extraordinary precision during development, but after injury, it often fails to repair itself. One major reason is that the molecular signals guiding axon growth […] Read More about Lei Gao