Hypertrophic cardiomyopathy (HCM) affects nearly 1 in 500 people in the US and causes the walls of the heart to thicken, leading to outcomes as severe as heart failure and […] Read More
In the Davis and Regnier Labs, Rachelle Soriano is helping to characterize human beta myosin mutation E525K to determine its effects on sarcomere contraction and organization. The characterization of this […] Read More
To improve the field’s understanding of MBNL1-directed transcriptome maturation, Kalen Robeson will use human iPSC models to determine the role of MBNL1 in differentiation into skeletal muscle and to determine […] Read More
As a postdoctoral fellow, Christian Mandrycky will test a hypothesis that MYH3 mutations (implicated in the skeletal muscle disorder Distal arthrogryposis) alter both the mechanics of the contractile apparatus as […] Read More