Stem Cells in Development and Regeneration

CONJ 530 – 3 Credits – Winter 2019

Date and Time: Tuesdays and Thursdays – 10:00-11:30am
Location: SLU, Building F, room F106
Instructors: Prof. Hannele Ruohola-Baker and Prof. Carol Ware

Course description

In this class we will discuss three topics: the recent findings on adult and embryonic stem cell classes and their niches, on epigenetic control of stem cells and stem cells in human disease.

Learning objectives

After this class, students should have a solid foundation on stem cell biology, epigenetic analysis and regulation of stem cells and human diseases connected to stem cell biology.

Course materials and/or textbooks

The course will go through recent seminal papers on stem cell biology.

Course requirements, examinations and grading

Students will develop a stem cell research proposal at the end of the quarter with the help of a chosen faculty member, write a one-page abstract on the idea and present the proposal to the class.

20% participation, including discussions on the papers
80% final project and presentation

Lecture Schedule

January 8 & January 10: Regeneration – Animals — SlidesReading, Reading SupplementQuestions, Slides
January 15 & January 17: Pluripotent Cells — SlidesReading, Questions
January 22 & January 24: Stem Cell Energetics — SlidesReading, Questions
January 29 & January 31: Stem Cell Epigenetics — Slides, Reading, Questions


February 5 & February 7: Regeneration – Sensory Cells — Slides
February 12 & February 14: Neural Development — Slides
February 19 & February 21: Neuro Disease Models/Organoids — Slides, Reading, Reading Supplement, Questions
February 26 & February 28: Cardio Development — SlidesReading, Questions


March 5 & March 7: Organoids — SlidesReading, Questions, Slides
March 12 & March 14: Finals — InstructionsPartners