RANK, the primary regulator of osteoclastogenesis, mediates the effects of denosumab, an anti-RANKL antibody that provides antiresorptive therapy to millions of people affected by conditions such as osteoporosis. The drug […] Read More
As an ISCRM REU intern, Catlyn Wetzel will employ CRISPR/Cas9 gene editing technologies to develop a promoterless gene trap cell line. Dr. Bengtsson’s lab is working on gene therapies for […] Read More
Clinical studies have linked anticholinergic drugs to dementia risk. However, it remains unclear whether this is due to the direct effects of these medications or a predisposition to dementia in […] Read More
In the Davis and Regnier Labs, Rachelle Soriano is helping to characterize human beta myosin mutation E525K to determine its effects on sarcomere contraction and organization. The characterization of this […] Read More
As a primarily cell-sparse and regionally-limited space, the meniscus has poor regenerative qualities after injury. As an ISCRM REU student in the Robinson Lab, Jordan Vanni is focusing on characterizing […] Read More
As an ISCRM REU Fellow, Birva Pinto will investigate the genetic mutation G159D in cardiac troponin C (cTnC) related to Dilated Cardiomyopathy (DCM), a disease that enlarges the heart chambers, […] Read More