Building on preliminary data showing that the gene efemp1 is dispensable for the first phase of spine mineralization—Rohda Yase will study the 2nd phase of skeletal development by determining the role […] Read More
As an ISCRM Undergraduate Fellow, Anika Ghelani will investigate the biomechanical role of the chaperone protein melusin in humans using engineered heart tissues (EHTs) created from wild-type hiPSC-CMs and hiPSC-CMs […] Read More
Funding will allow Dania Ahmed to test a hypothesis that restoring typical desmin levels in cardiomyopathic cells with the MYH7 E848G mutation – associated with dilated cardiomyopathy – will help […] Read More
With support from an ISCRM Fellowship, Jenny Nathans aims to further develop and deploy molecular recording for the precise reconstruction of signaling history in development. She will first establish this […] Read More
As an ISCRM Fellow, Elisa Clark will undertake a project aimed at improving efficacy of engineered T cell therapies against solid tumors using cytokine pre-treatment. Clark will test how cytokines […] Read More
In her fellowship project, Sophie Blackburn will generate glomerulus-like structures in vitro by recapitulating physiological growth confinement of kidney organoids during differentiation and induce vasculogenesis of endothelial cells across microfluidic […] Read More
Using zebrafish as an in vivo model, ISCRM Fellow Erik Black will advance research efforts underway to better understand the mechanisms underlying the transition from stem cells to specialized cells […] Read More
In collaboration with the Institute for Protein Design (IPD – UW), postdoctoral fellow Damien Detraux will use synthetic AI-designed proteins to robustly and specifically target signaling pathways though RTKs-modulating mini-binders […] Read More