How our bones develop influences our risk of osteoporosis and other skeletal disorders. In the Musculoskeletal Systems Biology Lab, led by Ronald Young Kwon, Hayden Bhavsar studies bone development by identifying genes expressed in osteoblasts and defining transcriptionally distinct subpopulations within the developing bone, using computational methods to integrate and analyze gene expression data. With the support of an ISCRM fellowship, he will establish a regenerative model and investigate how mechanical signaling shapes osteoblast gene expression at the interface between tendon and bone.
