Immunology
Associate Professor and Director of Mentor Education
Email: etwojno@uw.edu | Phone: 206.543.4167
Dr. Elia Tait Wojno and her team work on dissecting how immune and epithelial responses at mucosal barriers are regulated during helminth parasite infection and allergy, with a special emphasis on how cytokines and prostaglandins influence stem cell function to promote inflammation. Currently, we do not fully understand how immune and epithelial stem cells in the lung and intestine control altered tissue function and inflammation. We use in vitro and in vivo studies of immune, epithelial, and stem cell biology in mice and humans to identify basic mechanisms that underlie mucosal barrier inflammation and host protection against infection. These studies will reveal the importance of stem cell-mediated effects on promoting inflammation in tissues and have the potential to inform the development and use of new, stem cell-directed therapies to manage inflammatory conditions in the lung and gut.