Seattle Children’s Research Institute
Assistant Professor
Email: kimberly.aldinger@seattlechildrens.org | Phone: 206.884.1226
The developing cerebellum is highly vulnerable to damage, which can lead to neurological complications in children. This damage can be caused by genetic variants or by prenatal injuries, especially in regions with dense blood vessels. We are using induced pluripotent stem cell models to study how blood vessels and neurons interact to guide cerebellar development and how disruptions to these interactions contribute to cerebellar damage. Our goal is to inform strategies to prevent and treat cerebellar injuries, ultimately reducing the risk of significant neurodevelopmental disabilities in children.