Position: Research Scientist/Engineer 2 or 3
Department: Medicine, Division of Medical Genetics
Location: Health Sciences
FTE: 100%
Contact: Wendy Raskind, MD, PhD (wendyrun@uw.edu) or Olena Korvatska, PhD (ok5@uw.edu)
The Division of Medical Genetics has an exciting job opportunity for a Research Scientist/Engineer 2 or 3 with an interest in neurogenetics and neurobiology. The work involves functional analyses of disease-causing variants in various biological models, including induced pluripotent stem cells (iPCS) and tissues from patients with various hereditary neurologic diseases. The applicant should be a motivated, highly organized individual interested in learning/applying novel skills and techniques in this fast-moving field. The Research Scientist reports directly to the PI and is expected to work independently and collaboratively with a highly interactive group of fellow research personnel.
He/she must be able to work independently and have the ability to conceptualize, design, carry out, analyze, and interpret experiments with minimal oversight. This position may involve training and supervision of students. Initiative, problem solving ability, and willingness to learn and teach new procedures and techniques are therefore essential.
Duties:
- Support and participate in regulatory and certification processes and laboratory compliance
- Develop new laboratory techniques
- Train and supervise other staff members in new techniques
- Formulate hypotheses that can be tested experimentally
- Design and conduct experiments with minimal supervision
- Process data and analyze results
- Present ongoing work and findings at lab meetings
- Participate in preparation of manuscripts for publication
- Contribute to generation of proposals for funding
- Perform related duties as required
Qualifications: Master’s Degree in a biological science such as Molecular and Cellular Biology, Neurobiology, Genome Sciences or Immunology, with 2 years of experience required. PhD in related field with first authorship in at least one peer-reviewed publication and postdoctoral fellowship experience or equivalent experience preferred.
Required expertise: mammalian tissue culture, cell transfection, reporter assays, CRISPR/CAS9 genome editing, real-time RT-PCR, flow cytometry, fluorescence microscopy and image analysis, protein analysis by western blotting/ELISA.
Desired experience: establishing and/or differentiation of human iPSCs. Experience with nextgeneration DNA/RNA sequencing and data analyses is a plus.
Conditions of Employment: This position requires some flexibility of work schedule to accommodate experiments with fixed-time courses.