Genetics of cystogenesis in base-edited human organoids reveal therapeutic strategies for polycystic kidney disease

Cell Stem Cell, June 2024

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GAGE-seq concurrently profiles multiscale 3D genome organization and gene expression in single cells

Nature Genetics, May 2024

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Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration

PNAS, May 2024

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Machine learning-guided engineeringof genetically encoded fluorescentcalcium indicators

Nature Computational Biology, March 2024

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Single cell atlas of kidney cancer endothelial cells reveals distinct expression profiles and phenotypes

BJC Reports, March 2024

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Genetically Encoded XTEN-based Hydrogels with Tunable Viscoelasticity and Biodegradability for Injectable Cell Therapies

Advanced Science, March 2024

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MBNL1 Regulates Programmed Postnatal Switching Between Regenerative and Differentiated Cardiac States

Circulation, March 2024

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Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision

Immunity, February 2024

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De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity

PNAS, January 2024

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Pharmacologic enhancement of retromer rescues endosomal pathology induced by defects in the Alzheimer’s gene SORL1

Stem Cell Reports, December 2023

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