Kairui Jiang is developing aptamer-based tools to isolate specific cell populations from human iPSC-derived neuromuscular cultures. In the Pun and Mack labs, he will apply an NRP2-binding aptamer to enrich […] Read More
The muscle spindle is a skeletal muscle stretch receptor that is vital to proprioception, your body’s ability to sense its position in space. There are major gaps in our understanding […] Read More
Since their introduction in 2006, human iPSCs have enabled a generation of lineage-specific cell lines and organoids. However, bridging in vitro findings to whole-organism outcomes remains slow. Supported by an […] Read More
As a Bothell Fellow, Salvador Escamilla was part of a research team that attempted to better characterize a novel CRISPR edited iPSC line developed in the Mack Lab to model […] Read More
As a postdoctoral fellow, Christian Mandrycky will test a hypothesis that MYH3 mutations (implicated in the skeletal muscle disorder Distal arthrogryposis) alter both the mechanics of the contractile apparatus as […] Read More