Building on preliminary data showing that the gene efemp1 is dispensable for the first phase of spine mineralization—Rohda Yase will study the 2nd phase of skeletal development by determining the role […] Read More
In the Cardiac Systems Simulation Lab, Jamie Yang is evaluating the potential effects of optogenetic stimulation in studying and mitigating engraftment-associated arrhythmias (EAs) using computational modeling. In her project, she […] Read More
Funding will allow Dania Ahmed to test a hypothesis that restoring typical desmin levels in cardiomyopathic cells with the MYH7 E848G mutation – associated with dilated cardiomyopathy – will help […] Read More
With a long-term goal of improving dental health outcomes, ISCRM Fellow Anjali Patni will generate functional enamel layer in order to study the congenital tooth disorder amelogenesis imperfecta (AI) and […] Read More
With support from an ISCRM Fellowship, Jenny Nathans aims to further develop and deploy molecular recording for the precise reconstruction of signaling history in development. She will first establish this […] Read More
As an ISCRM Fellow, Elisa Clark will undertake a project aimed at improving efficacy of engineered T cell therapies against solid tumors using cytokine pre-treatment. Clark will test how cytokines […] Read More
In her fellowship project, Sophie Blackburn will generate glomerulus-like structures in vitro by recapitulating physiological growth confinement of kidney organoids during differentiation and induce vasculogenesis of endothelial cells across microfluidic […] Read More
As a postdoctoral fellow, Christian Mandrycky will test a hypothesis that MYH3 mutations (implicated in the skeletal muscle disorder Distal arthrogryposis) alter both the mechanics of the contractile apparatus as […] Read More
In collaboration with the Institute for Protein Design (IPD – UW), postdoctoral fellow Damien Detraux will use synthetic AI-designed proteins to robustly and specifically target signaling pathways though RTKs-modulating mini-binders […] Read More