As an ISCRM REU intern, Catlyn Wetzel will employ CRISPR/Cas9 gene editing technologies to develop a promoterless gene trap cell line. Dr. Bengtsson’s lab is working on gene therapies for […] Read More
My doctoral research investigates how a small RNA molecule, microRNA-192, guides human stem cells toward a pancreatic beta cell fate. Using a CRISPR-Cas9-engineered, inducible miRNA system, I aim to improve […] Read More
With support from the ISCRM Fellowship, Theresa is developing two complementary high-throughput single-cell techniques to investigate disease-associated enhancers in retinal organoids. Enhancers—noncoding DNA elements that regulate gene expression—have been linked to […] Read More
With an ISCRM fellowship award, Brenda Garibay investigates whether HP1BP3, an H1-like histone protein, is essential for epigenetic memory in heterochromatin. Using human iPSCs, she aims to uncover how HP1BP3 […] Read More
With ISCRM fellowship funding, Willow Chernoske will develop and conduct a proof of concept for a CRISPR-Cas12a biotinylation system designed by the Escobar Lab to determine the epigenetic mechanisms that […] Read More