As a postdoctoral fellow, Riya Keshri will be developing treatment for various muscle atrophies including Sarcopenia using synthetic AI-designed proteins. Dr. Keshri will be identifying synthetic designed binders against RTKs/RSTKs that can robustly promote direct reprograming of fibroblast into skeletal muscles. In collaboration with the Institute of Protein Design, she will be forcing non-pairing receptors in a complex using synthetic AI-designed designed binders to induce novel unprecedented signaling pathways that will ultimately change the cell fate to muscles. The project aims to drive advancements in personalized regenerative medicine with usage of powerful AI-designed proteins.