← Back to Faculty

Suman Jayadev MD

Associate Professor

Email: sumie@uw.edu | Phone: 206.221.2930

Our laboratory is interested in cell autonomous and non-cell autonomous pathways contributing to neurodegeneration with a particular focus on the role of neuroimmune mechanisms in disease.  We differentiate iPSCs from patients with monogenic and sporadic forms of neurodegenerative syndromes into various central nervous system cell types including neurons and microglia.  We can employ both single cell-type culture and mixed cultures to test mechanism based hypotheses and further our understanding of disease pathogenesis.  With these tools we hope to dissect the relevant cellular pathways that contribute to developing neurological disease and thus facilitate our identification of druggable therapeutic targets.