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Audrey Hayes

Vascular stability – the capacity of mature endothelium to maintain barrier integrity, resist aberrant sprouting, and support proper perfusion – is essential for tissue homeostasis. Loss of vascular stability is […] Read More

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Madhavi Karthik

Tadpoles of closely related frog species Xenopus laevis and Xenopus tropicalis exhibit varying capacities of regenerative success depending on their developmental stage and structure type, making them an excellent model for tissue regeneration. Previous […] Read More

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Kazuma Fukuda

One of the critical processes in developing and regenerating organs is endoreplication: DNA synthesis without cell division. Despite its potential to increase cell size, whether and how endoreplication influences organ […] Read More

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Priscilla Boatemaa

Left-right (L-R) patterning is essential for proper organ development, and its disruption causes heterotaxy, an abnormal arrangement of internal organs, often accompanied by congenital heart defects. Although loss of the […] Read More

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Caleb Kono

Skeletal muscle has an extraordinary ability to regenerate, but this process declines sharply with age and disease, leading to weakness and frailty. A major challenge is that the genetic programs […] Read More

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Alex Elbahr

With the support of the ISCRM Fellowship, Alex Elbahr will delineate the proteolytic processing of Nucleophosmin (NPM1) in hematopoietic stem cells (HSCs), employing recombinant NPM1 constructs and targeted protease assays. […] Read More

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Rachelle Soriano

In the Davis and Regnier Labs, Rachelle Soriano is helping to characterize human beta myosin mutation E525K to determine its effects on sarcomere contraction and organization. The characterization of this […] Read More

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Lily Nguyen

As an ISCRM Undergraduate Fellow, Lily Nguyen aims to address the role of two core signaling pathways (Notch and Hedgehog) in maintaining the structural integrity of the developing nervous system. […] Read More

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Riya Keshri

As a postdoctoral fellow, Riya Keshri will be developing treatment for various muscle atrophies including Sarcopenia using synthetic AI-designed proteins. Dr. Keshri will be identifying synthetic designed binders against RTKs/RSTKs […] Read More

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Manith Atapattu

With ISCRM Fellowship funding, Manith will investigate the role of a microRNA called miR9-2, an important genetic regulator in brain development. Using a mouse model the Cherry Lab has generated, […] Read More