With ISCRM Fellowship funding, Manith will investigate the role of a microRNA called miR9-2, an important genetic regulator in brain development. Using a mouse model the Cherry Lab has generated, […] Read More
With ISCRM fellowship funding, Willow Chernoske will develop and conduct a proof of concept for a CRISPR-Cas12a biotinylation system designed by the Escobar Lab to determine the epigenetic mechanisms that […] Read More
As an ISCRM Fellow, Hailemikael Yirdaw will develop and test designed protein scaffolds that greatly enhance the sensitivity of CAR T cells to tumor antigens. Achieving a new generation of […] Read More
An ISCRM fellowship will allow Lauren D’Amico to study sarcomeric mutations that cause alterations to tension-time index (TTI). Understanding how these variations are linked to disruption in the force-generation capacity […] Read More
ISCRM fellowship funding will enable Leona Binyam-Temelso to identify the minimal set of gene edits possible to generate human pluripotent stem cell-derived cardiomyocytes that will not produce arrhythmias once transplanted […] Read More
Building on preliminary data showing that the gene efemp1 is dispensable for the first phase of spine mineralization—Rohda Yase will study the 2nd phase of skeletal development by determining the role […] Read More
In the Cardiac Systems Simulation Lab, Jamie Yang is conducting a computational study to establish the feasibility of using optogenetic stimulation to suppress ventricular arrhythmias associated with human pluripotent stem […] Read More
As an ISCRM Undergraduate Fellow, Anika Ghelani will investigate the biomechanical role of the chaperone protein melusin in humans using engineered heart tissues (EHTs) created from wild-type hiPSC-CMs and hiPSC-CMs […] Read More