With the support of the ISCRM Fellowship, Alex Elbahr will delineate the proteolytic processing of Nucleophosmin (NPM1) in hematopoietic stem cells (HSCs), employing recombinant NPM1 constructs and targeted protease assays. […] Read More
With funding from the ISCRM Undergraduate Fellowship, Sahana Subramanian will identify healthy and unhealthy endothelial cell flow conditions within a perfusable engineered heart tissue, hypothesizing that physiologically relevant shear stress […] Read More
As an ISCRM Undergraduate Fellow, Lily Nguyen aims to address the role of two core signaling pathways (Notch and Hedgehog) in maintaining the structural integrity of the developing nervous system. […] Read More
With ISCRM Fellowship funding, Manith will investigate the role of a microRNA called miR9-2, an important genetic regulator in brain development. Using a mouse model the Cherry Lab has generated, […] Read More
With ISCRM fellowship funding, Willow Chernoske will develop and conduct a proof of concept for a CRISPR-Cas12a biotinylation system designed by the Escobar Lab to determine the epigenetic mechanisms that […] Read More
As an ISCRM Fellow, Hailemikael Yirdaw will develop and test designed protein scaffolds that greatly enhance the sensitivity of CAR T cells to tumor antigens. Achieving a new generation of […] Read More
An ISCRM fellowship will allow Lauren D’Amico to study sarcomeric mutations that cause alterations to tension-time index (TTI). Understanding how these variations are linked to disruption in the force-generation capacity […] Read More
ISCRM fellowship funding will enable Leona Binyam-Temelso to identify the minimal set of gene edits possible to generate human pluripotent stem cell-derived cardiomyocytes that will not produce arrhythmias once transplanted […] Read More
Building on preliminary data showing that the gene efemp1 is dispensable for the first phase of spine mineralization—Rohda Yase will study the 2nd phase of skeletal development by determining the role […] Read More