As an ISCRM Fellow, Scott Schactler is characterizing the microenvironment of the lncRNA Xist during X-chromosome inactivation using photocatalyst-powered super-resolution proximity-labeling tools. Using Oligonucleotide-directed proximity-interactome MAPing (O-MAP) in a cell […] Read More
Unlike non-mammalian vertebrates, hair cell damage in the mature mammalian cochlea leads to permanent hearing loss. There is great need for the discovery of new factors that promote hair cell […] Read More
In his fellowship project, Brad will investigate methods to generate spermatogonial cells (the base cell of spermatogenesis) from induced pluripotent stem cells using directed stem cell differentiation alongside a complex […] Read More
ISCRM fellowship funds will enable Morgan Jones to determine how a poised chromatin state is initially formed as well as how terminal effector and memory precursor CD8+ T cells maintain […] Read More
To improve the field’s understanding of MBNL1-directed transcriptome maturation, Kalen Robeson will use human iPSC models to determine the role of MBNL1 in differentiation into skeletal muscle and to determine […] Read More
With her ISCRM fellowship, Brizzia Munoz Robles will develop a generalizable strategy to customize the biochemical properties of cell-laden biomaterials in 4D through functional protein photoassembly. The goal is to […] Read More
Heber Lara will use ISCRM fellowship funds to uncover the role of a growth factor in the small intestinal epithelium. His aims are to establish this growth factor as an […] Read More
Funding will allow Ross Bretherton to explore the role of dilated cardiomyopathy and cardiac fibrosis in heart failure. In his investigation, Bretherton will characterize crosstalk between cardiomyocytes, cardiac fibroblasts, and […] Read More