Ramila Gulieva
Current human kidney organoid models, derived from pluripotent stem cells, face significant limitations. They remain structurally immature, functionally incomplete, and often highly variable between batches, lacking the vascularization and specialized […] Read More about Ramila Gulieva
Caleb Kono
Skeletal muscle has an extraordinary ability to regenerate, but this process declines sharply with age and disease, leading to weakness and frailty. A major challenge is that the genetic programs […] Read More about Caleb Kono
Divya Avnoor
Since their introduction in 2006, human iPSCs have enabled a generation of lineage-specific cell lines and organoids. However, bridging in vitro findings to whole-organism outcomes remains slow. Supported by an […] Read More about Divya Avnoor
Theresa Chen
With support from the ISCRM Fellowship, Theresa is developing two complementary high-throughput single-cell techniques to investigate disease-associated enhancers in retinal organoids. Enhancers—noncoding DNA elements that regulate gene expression—have been linked to […] Read More about Theresa Chen
Dorice Goune
Liver disease causes millions of deaths each year, yet scientists still lack the detailed structural information needed to 3D print a working liver. With support from ISCRM Fellowship, Dorice Goune […] Read More about Dorice Goune
Charlie Thel
Like other organs, the heart forms scar tissue in response to stress or injury. Cardiac fibroblasts are the cells in the heart responsible for regulating production and degradation of scar […] Read More about Charlie Thel
Lei Gao
Our nervous system is wired with extraordinary precision during development, but after injury, it often fails to repair itself. One major reason is that the molecular signals guiding axon growth […] Read More about Lei Gao
Janie Johnson
Biological sex plays a role in meniscus injury and regeneration: females experience more tears and worse repair outcomes. As a first year graduate student in the Robinson Lab, Janie Johnson […] Read More about Janie Johnson
Brenda Garibay
With an ISCRM fellowship award, Brenda Garibay investigates whether HP1BP3, an H1-like histone protein, is essential for epigenetic memory in heterochromatin. Using human iPSCs, she aims to uncover how HP1BP3 […] Read More about Brenda Garibay
Sarah John
With support from the ISCRM fellowship, Sarah John aims to investigate how the dysfunction of TAOK1 kinase results in perturbed early brain development and macrocephaly. Sarah will utilize hiPSCs harboring […] Read More about Sarah John