Caleb Kono
Skeletal muscle has an extraordinary ability to regenerate, but this process declines sharply with age and disease, leading to weakness and frailty. A major challenge is that the genetic programs […] Read More
Divya Avnoor
Since their introduction in 2006, human iPSCs have enabled a generation of lineage-specific cell lines and organoids. However, bridging in vitro findings to whole-organism outcomes remains slow. Supported by an […] Read More
Theresa Chen
With support from the ISCRM Fellowship, Theresa is developing two complementary high-throughput single-cell techniques to investigate disease-associated enhancers in retinal organoids. Enhancers—noncoding DNA elements that regulate gene expression—have been linked to […] Read More
Dorice Goune
Liver disease causes millions of deaths each year, yet scientists still lack the detailed structural information needed to 3D print a working liver. With support from ISCRM Fellowship, Dorice Goune […] Read More
Charlie Thel
Like other organs, the heart forms scar tissue in response to stress or injury. Cardiac fibroblasts are the cells in the heart responsible for regulating production and degradation of scar […] Read More
Janie Johnson
Biological sex plays a role in meniscus injury and regeneration: females experience more tears and worse repair outcomes. As a first year graduate student in the Robinson Lab, Janie Johnson […] Read More
Brenda Garibay
With an ISCRM fellowship award, Brenda Garibay investigates whether HP1BP3, an H1-like histone protein, is essential for epigenetic memory in heterochromatin. Using human iPSCs, she aims to uncover how HP1BP3 […] Read More
Sarah John
With support from the ISCRM fellowship, Sarah John aims to investigate how the dysfunction of TAOK1 kinase results in perturbed early brain development and macrocephaly. Sarah will utilize hiPSCs harboring […] Read More
Jasmine Villegas
Cystic Fibrosis (CF) is a life-limiting genetic disease caused by a mutation of CFTR, eventually leading to respiratory failure. With an ISCRM fellowship award, Jasime Villegas aims to create a CRISPR-Cas9 […] Read More