With support from the ISCRM fellowship, Sarah John aims to investigate how the dysfunction of TAOK1 kinase results in perturbed early brain development and macrocephaly. Sarah will utilize hiPSCs harboring […] Read More
Cystic Fibrosis (CF) is a life-limiting genetic disease caused by a mutation of CFTR, eventually leading to respiratory failure. With an ISCRM fellowship award, Jasime Villegas aims to create a CRISPR-Cas9 […] Read More
As an ISCRM Fellow, Scott Schactler is characterizing the microenvironment of the lncRNA Xist during X-chromosome inactivation using photocatalyst-powered super-resolution proximity-labeling tools. Using Oligonucleotide-directed proximity-interactome MAPing (O-MAP) in a cell […] Read More
Unlike non-mammalian vertebrates, hair cell damage in the mature mammalian cochlea leads to permanent hearing loss. There is great need for the discovery of new factors that promote hair cell […] Read More
In his fellowship project, Brad will investigate methods to generate spermatogonial cells (the base cell of spermatogenesis) from induced pluripotent stem cells using directed stem cell differentiation alongside a complex […] Read More
ISCRM fellowship funds will enable Morgan Jones to determine how a poised chromatin state is initially formed as well as how terminal effector and memory precursor CD8+ T cells maintain […] Read More
To improve the field’s understanding of MBNL1-directed transcriptome maturation, Kalen Robeson will use human iPSC models to determine the role of MBNL1 in differentiation into skeletal muscle and to determine […] Read More
With her ISCRM fellowship, Brizzia Munoz Robles will develop a generalizable strategy to customize the biochemical properties of cell-laden biomaterials in 4D through functional protein photoassembly. The goal is to […] Read More