As a Postdoctoral Fellow, McCloskey is part of a team developing gene therapeutics to treat Amyotrophic Lateral Sclerosis (ALS), a fatal neuromuscular disease. In order to combat challenges in drug […] Read More
With the support of the ISCRM Fellowship, Alex Elbahr will delineate the proteolytic processing of Nucleophosmin (NPM1) in hematopoietic stem cells (HSCs), employing recombinant NPM1 constructs and targeted protease assays. […] Read More
Clinical studies have linked anticholinergic drugs to dementia risk. However, it remains unclear whether this is due to the direct effects of these medications or a predisposition to dementia in […] Read More
In the Davis and Regnier Labs, Rachelle Soriano is helping to characterize human beta myosin mutation E525K to determine its effects on sarcomere contraction and organization. The characterization of this […] Read More
With support from the ISCRM fellowship, Sarah John aims to investigate how the dysfunction of TAOK1 kinase results in perturbed early brain development and macrocephaly. Sarah will utilize hiPSCs harboring […] Read More
With funding from the ISCRM Undergraduate Fellowship, Sahana Subramanian will identify healthy and unhealthy endothelial cell flow conditions within a perfusable engineered heart tissue, hypothesizing that physiologically relevant shear stress […] Read More
As a primarily cell-sparse and regionally-limited space, the meniscus has poor regenerative qualities after injury. As an ISCRM REU student in the Robinson Lab, Jordan Vanni is focusing on characterizing […] Read More
As an ISCRM-Bothell Fellow, Christian Paulos will conduct research with the Sniadecki and Qu Labs, where is working on developing engineered human induced pluripotent stem cell-derived tendon constructs as an […] Read More
As an ISCRM REU Fellow, Birva Pinto will investigate the genetic mutation G159D in cardiac troponin C (cTnC) related to Dilated Cardiomyopathy (DCM), a disease that enlarges the heart chambers, […] Read More
As an ISCRM Undergraduate Fellow, Lily Nguyen aims to address the role of two core signaling pathways (Notch and Hedgehog) in maintaining the structural integrity of the developing nervous system. […] Read More