Panel A shows a scatter plot of compounds by sensitivity in AML blasts and LSCs, with blast-specific, LSC-specific, and non-specific drugs colored. Panel B shows a heatmap of inhibition by AML blast-specific compounds in AML blasts and LSCs.

Potential Seen for Tailoring Acute Myeloid Leukemia Treatment

December 3, 2018 | Categories: Announcements, Research | Tagged: , ,

Drug response screening of leukemia stem cells offers clues to relapse and suggests ways to improve patient-specific therapies Advances in rapid screening of leukemia cells for drug susceptibility and resistance […] Read More

Four circular cells are shown on a black background, each highlighted in different fluorescent colors: yellow-purple (top left), blue (top right), green (bottom left), and red (bottom right).

Study: Using big data to help fight a deadly cancer

January 12, 2018 | Categories: Research | Tagged: , ,

Researchers built an algorithm to discern which drugs might best combat patients’ individual cases of acute myeloid leukemia. The statistics are grim. For patients fighting an aggressive form of leukemia known as acute myeloid leukemia, or AML, doctors over the last 40 years have usually used a combination of two drugs to fight the disease, but it seldom cures it. Read More

Two smiling adults with glasses, one man in a suit jacket and one woman in a gray top, stand together in a laboratory setting with shelves of scientific equipment and supplies in the background.

Cancer trial: Expectation-setting gives way to hope

September 27, 2017 | Categories: Research | Tagged: , ,

Beginning four years ago, 15 women with incurable (metastatic triple-negative) breast cancer were enrolled in a unique clinical trial. It explored one concept of “precision medicine” – the suggestion that the brain power of multiple medical experts and the collection of an immense volume of data about each woman’s condition would yield the most personalized, customized care possible. Read More

"The contribution of the women enrolling in this trial is invaluable and their decision to participate

Study’s ‘panomic’ approach to advanced breast cancer

March 3, 2014 | Categories: Research | Tagged: , , ,

Trial enrollees sought; effort involves sharing tumors’ responses to therapy in massive public online database. Ten women with advanced breast cancer will participate in one of the most intensive clinical trials ever […] Read More