Two groups of stained neutrophil cells: the left group shows normal-shaped nuclei, while the right group shows nuclei with abnormal shapes, indicating lamin B1 deletion (Pelger-Huët anomaly).

Deletion of Lamin B1 Linked to Nuclear Abnormalities Seen in Cancer

March 11, 2022 | Categories: Research, Uncategorized | Tagged: , ,

Using gene-editing tools to decrease expression of lamin B1 in two stem cell models, the researchers show that deletion of lamin B1 causes change in stem cell function and nuclear shape – and contributes to leukemia progression. Read More