Using gene-editing tools to decrease expression of lamin B1 in two stem cell models, the researchers show that deletion of lamin B1 causes change in stem cell function and nuclear shape – and contributes to leukemia progression. Read More
Acute lymphocytic leukemia (ALL) is the most common type of childhood cancer, representing approximately 25% of cancer diagnoses in children 0-15. More than 3,000 new cases of ALL are diagnosed every year in the United States - and the incidence rate is rising. Read More