Helper or Culprit: Re-Examining the Role of Fibroblasts in Dilated Cardiomyopathy

September 11, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , , , , ,

In a paper published in Science, a multidisciplinary ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring.  Read More

What Constitutes Appropriate Scientific Justification in Stem Cell Research?

June 12, 2025 | Categories: Uncategorized

A multi-institutional team convened by the International Society for Stem Cell Research (ISSCR) elaborates on the meaning of “appropriate scientific justification” for review boards, regulators, and scientists who evaluate and conduct stem cell research. Read More

Meet the 2025 Tietze Award Winners

May 6, 2025 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , ,

Smita Yadav and Nobuhiko (Nobu) Hamazaki have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity

April 30, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More

New Platform for Tissue Engineers Reduces Guesswork in Bioink Formulation

April 11, 2025 | Categories: Core Faculty, Uncategorized | Tagged: , ,

The Stevens Lab has unveiled a game-changing system to simultaneously screen dozens of varying compositions of bioinks for tissue and organ printing Read More

Reh Lab Shows Conclusively that AAV-delivered Genes Can Regenerate Mammalian Retinal Neurons

March 24, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina Read More

Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart

May 2, 2024 | Categories: Research, Uncategorized | Tagged: , , ,

An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More

Stem Cells in Clinical Trials

April 1, 2024 | Categories: Uncategorized

On Thursday, March 6, ISCRM hosted Stem Cells in Clinical Trials: A Panel Discussion on Progress in the Field of Regenerative Medicine. Summaries of the presentations and a recording of the event are now available. Read More

Zheng Lab Unveils Platform for Modeling Cerebral Malaria in 3D

November 20, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

A new paper from the Zheng Lab, published in Cell Reports, unveils a technique for probing cerebral malaria inflammation in 3D engineered human brain microvessels. Read More

Stem Cell-derived Organoids Secrete Tooth Enamel Proteins

August 14, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers led by Hannele Ruohola-Baker have created organoids from stem cells that secrete the proteins that form the enamel that protects our teeth from damage and decay. Read More