Two women work together in a laboratory. One, wearing a lab coat and gloves, points at equipment on the bench, while the other, in glasses and a plaid shirt, observes attentively. Shelves with lab supplies line the background.

Helper or Culprit: Re-Examining the Role of Fibroblasts in Dilated Cardiomyopathy

September 11, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , , , , ,

In a paper published in Science, a multidisciplinary ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring.  Read More

A person wearing light purple gloves holds a clear petri dish containing a pink substance, suggesting a laboratory or scientific setting.

What Constitutes Appropriate Scientific Justification in Stem Cell Research?

June 12, 2025 | Categories: Uncategorized

A multi-institutional team convened by the International Society for Stem Cell Research (ISSCR) elaborates on the meaning of “appropriate scientific justification” for review boards, regulators, and scientists who evaluate and conduct stem cell research. Read More

Two people are shown side by side. On the left, a woman with long dark hair is wearing a coral top and smiling. On the right, a man with short dark hair is wearing a blue shirt and smiling against a white background.

Meet the 2025 Tietze Award Winners

May 6, 2025 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , ,

Smita Yadav and Nobuhiko (Nobu) Hamazaki have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

A small, translucent, 3D-printed plastic object with a rectangular base, two vertical supports, and an oval-shaped top piece, placed on a gray surface.

User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity

April 30, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , ,

The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More

A gloved hand holds two clear plastic squares containing rows of colorful dots, likely samples or wells, inside a petri dish. The background and glove are tinted blue.

New Platform for Tissue Engineers Reduces Guesswork in Bioink Formulation

April 11, 2025 | Categories: Core Faculty, Uncategorized | Tagged: , ,

The Stevens Lab has unveiled a game-changing system to simultaneously screen dozens of varying compositions of bioinks for tissue and organ printing Read More

Microscope image of a worm section showing cells outlined in gray, with red and green fluorescent markers highlighting specific features along the outer edge of the body.

Reh Lab Shows Conclusively that AAV-delivered Genes Can Regenerate Mammalian Retinal Neurons

March 24, 2025 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers in the Reh Lab have produced the clearest evidence yet that AAV-delivered genes can stimulate regeneration in the mammalian retina Read More

Illustration of microscopic muscle fibers and proteins, showing bundled orange filaments with spiral extensions and rows of green and purple molecules, representing molecular processes within muscle tissue.

Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart

May 2, 2024 | Categories: Research, Uncategorized | Tagged: , , ,

An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More

Nine people sit at the front of a lecture hall while a woman stands and presents a Parkinsons disease research slide with trial details and results projected on a screen behind them.

Stem Cells in Clinical Trials

April 1, 2024 | Categories: Uncategorized

On Thursday, March 6, ISCRM hosted Stem Cells in Clinical Trials: A Panel Discussion on Progress in the Field of Regenerative Medicine. Summaries of the presentations and a recording of the event are now available. Read More

Diagram illustrating 3D brain microvessels under different conditions: resting, after 8 hours with TNF, and after 8 and 24 hours with parasites, showing changes like microparticles, gaps, filaments, and ghost cells.

Zheng Lab Unveils Platform for Modeling Cerebral Malaria in 3D

November 20, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

A new paper from the Zheng Lab, published in Cell Reports, unveils a technique for probing cerebral malaria inflammation in 3D engineered human brain microvessels. Read More

Fluorescent microscopy image of a tissue section showing a triangular structure with layers of blue, green, yellow, and magenta cells. Blue dots, likely cell nuclei, are scattered throughout. A scale bar indicates 50 micrometers.

Stem Cell-derived Organoids Secrete Tooth Enamel Proteins

August 14, 2023 | Categories: Core Faculty, Research, Uncategorized | Tagged: , , ,

Researchers led by Hannele Ruohola-Baker have created organoids from stem cells that secrete the proteins that form the enamel that protects our teeth from damage and decay. Read More