How Cellular Dysfunction Associated with Alzheimer’s Disease Arises in Microglia
April 17, 2025 | Categories: Core Faculty |New research from the lab of ISCRM faculty member Jessica Young sheds light on the relationship between loss of SORL1 and Alzheimer's disease risk specifically in microglia. Read More
NIH Grant Advances Alzheimer’s Research – And Launches a Career
March 28, 2023 | Categories: Award, Core Faculty, Uncategorized |Tiara Schwarze-Taufiq, an ISCRM undergraduate fellow in 2021, is now a Research Scientist in the Young Lab thanks to an NIH R21 grant made possible in part by her own research. Read More
ISCRM Researchers Part of $56 Million Grant to Fund Alzheimer’s Research
September 3, 2021 | Categories: Core Faculty |The five-year grant awarded to the Kaiser Adult Changes in Thought study (ACT) will fund six cores and three interrelated research projects. Read More
Young Lab Links Loss of SORL1 Gene to Increased Alzheimer’s Risk
June 2, 2020 | Categories: Research |To overcome the inherent challenges in studying the brain, one ISCRM team used stem cell technology to implicate a gene known as SORL1 in some types of Alzheimer’s and to shed new light on why many promising treatments for this disease have hit dead ends in clinical trials. Read More
Stem-cell study points to new approach to Alzheimer’s disease
March 1, 2018 | Categories: Research |Improving the trafficking of cellular proteins in brain cells holds possibilities for new treatments and even prevention for Alzheimer’s disease, results of a new study suggest. Researchers found that a compound that enhances the shuttling of proteins within cells reduced the production of forerunners of two proteins implicated in brain cell death. Read More