Fluorescent microscopic image of EpiBinders-treated stem cells, showing clusters with cells stained in green, red, and blue, indicating different cellular components or markers. Text reads: EpiBinders-treated Stem Cells.

New $8.6M NIH RC2 Grant for an Interdisciplinary Team of ISCRM Faculty.

October 6, 2025 | Categories: Award, Core Faculty | Tagged: , , , , , , ,

An interdisciplinary team of ISCRM researchers has received an $8.6 million grant from the NIH to accelerate cell therapies for diabetes by achieving more reliable and reproducible generation of fully functional pancreatic islets from multiple stem cell lines. Read More

Three women wearing lab coats and face masks stand with arms crossed in a laboratory, with lab equipment and shelves visible around them and large windows in the background.

Regulating Cells With Designed Proteins

March 1, 2022 | Categories: Core Faculty, Research | Tagged: , , , ,

ISCRM researchers have developed a tool to selectively control the PRC2 complex – an epigenetic regulator that influences cell fate across multiple stages of development. That tool is a computer-designed protein binder engineered in partnership with the Institute for Protein Design (IPD). Read More