New $8.6M NIH RC2 Grant for an Interdisciplinary Team of ISCRM Faculty.
October 6, 2025 | Categories: Award, Core Faculty |An interdisciplinary team of ISCRM researchers has received an $8.6 million grant from the NIH to accelerate cell therapies for diabetes by achieving more reliable and reproducible generation of fully functional pancreatic islets from multiple stem cell lines. Read More
Regulating Cells With Designed Proteins
March 1, 2022 | Categories: Core Faculty, Research |ISCRM researchers have developed a tool to selectively control the PRC2 complex – an epigenetic regulator that influences cell fate across multiple stages of development. That tool is a computer-designed protein binder engineered in partnership with the Institute for Protein Design (IPD). Read More
ISCRM Research Sheds New Light on COVID-19 and Kidney Health
December 2, 2021 | Categories: Core Faculty, Research, Uncategorized |ISCRM researchers use kidney organoids to demonstrate that COVID-19 is capable of infecting kidney cells directly and test whether a synthetic protein designed by the Institute for Protein Design (IPD) might be capable of preventing infection. Read More
Supercharging Antibodies for Better Medicine
April 2, 2021 | Categories: Uncategorized |Researchers from the Ruohola-Baker Lab have collaborated with the Institute for Protein Design on a technology in which designed proteins assemble antibodies in nanocage structures, increasing their potency against cancer, COVID-19, and other diseases. Read More
Move over Gucci; researchers create designer stem cells
September 1, 2017 | Categories: Research |UW Medicine researchers recently lead a successful effort to create “designer” stem cells that might lead to advances in cancer and aging, they say. In a paper published in the journal PNAS, the scientists showed for the first time that a computer-generated protein can be inserted into stem cells to change their epigenetic memory, whose role is to ensure that a cell’s DNA sequence remains intact as it divides. Read More