Primary cilia (red) lining the surface of human kidney organoids (gray).

Freedman Lab Explores the Role Cilia Play in Signaling, Cell Fate, and Disease Development

April 27, 2022 | Categories: Research | Tagged: , , , , , ,

In the Freedman Lab, knocking out primary cilia reveals insights about the role the organelles play in cell fate and disease development. Read More

Regulating Cells With Designed Proteins

March 1, 2022 | Categories: Core Faculty, Research | Tagged: , , , ,

ISCRM researchers have developed a tool to selectively control the PRC2 complex – an epigenetic regulator that influences cell fate across multiple stages of development. That tool is a computer-designed protein binder engineered in partnership with the Institute for Protein Design (IPD). Read More

Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration

June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized | Tagged: , , ,

New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More