A smiling man with short brown hair and glasses, wearing a dark shirt and lanyard, stands indoors in front of a window with green foliage visible outside.

FDA Approves Gene Therapy with ISCRM Origins

July 5, 2023 | Categories: Core Faculty, Research | Tagged: , , ,

The FDA has approved a first-ever gene therapy for Duchenne muscular dystrophy based in part on technology developed by UW Medicine/ISCRM Researchers Read More

Two people are shown side by side. On the left, a woman with shoulder-length brown hair sits at a desk, smiling, with papers in front of her. On the right, a man with short hair smiles while sitting in an office.

Meet the 2023 Tietze Award Winners

June 1, 2023 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , , ,

Julie Mathieu, PhD and Niclas Bengtsson, PhD have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More

Primary cilia (red) lining the surface of human kidney organoids (gray).

Freedman Lab Explores the Role Cilia Play in Signaling, Cell Fate, and Disease Development

April 27, 2022 | Categories: Research | Tagged: , , , , , ,

In the Freedman Lab, knocking out primary cilia reveals insights about the role the organelles play in cell fate and disease development. Read More

Three women wearing lab coats and face masks stand with arms crossed in a laboratory, with lab equipment and shelves visible around them and large windows in the background.

Regulating Cells With Designed Proteins

March 1, 2022 | Categories: Core Faculty, Research | Tagged: , , , ,

ISCRM researchers have developed a tool to selectively control the PRC2 complex – an epigenetic regulator that influences cell fate across multiple stages of development. That tool is a computer-designed protein binder engineered in partnership with the Institute for Protein Design (IPD). Read More

Three scientists wearing lab coats, gloves, and face masks review notes in a laboratory. Shelves with colorful binders and lab equipment are visible in the background.

Gene Editing May Help Address Arrhythmia Challenges in Heart Regeneration

June 21, 2021 | Categories: Heart Regeneration, Research, Uncategorized | Tagged: , , ,

New data presented by ISCRM Director Chuck Murry suggests gene-editing may be the key to clearing a major hurdle for researchers hoping to remuscularize injured hearts with stem cell-derived cardiomyocytes Read More