A man in a white lab coat kneels next to a black dog on a leash in a white-walled room with colorful padded blocks and a yellow mat on the floor.

Favorable interim results reported in stem-cell therapy trial

January 8, 2018 | Categories: Research | Tagged: , , ,

A therapy developed at UW shows promise in its first test in young boys who have an inherited deadly muscle disease. Favorable interim results have been announced in a small clinical trial of a stem-cell therapy to treat patients with a rare, deadly disease called myotubular myopathy. Read More

A paper with the words Myotubular Myopathy is partly obscured by shadows. The KIRO 7 news logo appears in the bottom right corner.

Gene replacement therapy that works in dogs to be tested in children

May 18, 2017 | Categories: Research | Tagged: , , , ,

SEATTLE – KIRO 7 has learned of a revolutionary treatment, here in Seattle, that has saved the lives of dogs and is just months away from being tested in children. In […] Read More

Transfer of the MTM1 gene into the weakened muscle tissue of dogs affected by myotubular myopathy restores muscle strength. The disease arises from a genetic mutation that disrupts the production of a protein needed for muscle function.

Gene therapy treats muscle-wasting disease in dogs

February 15, 2017 | Categories: Research | Tagged: , , ,

Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease. UW Medicine Institute for Stem Cell […] Read More

Runners in athletic gear start a race under a “Seattle Marathon” banner, with a UW Medicine Sports, Spine & Orthopedic Health sign in the foreground. Trees without leaves and cloudy skies are visible.

UW, family rewriting neuromuscular research

November 23, 2016 | Categories: Announcements | Tagged: , ,

Physicians and researchers at the UW Medicine Institute for Stem Cell and Regenerative Medicine have partnered up with a nonprofit foundation in one of the leading efforts to find a cure […] Read More

Book cover with a blue background. Title: Regenerative Medicine for Degenerative Muscle Diseases. Editor: Martin K. Childers. Series title at the top: Stem Cell Biology and Regenerative Medicine.

New book published on regenerative medicine for degenerative muscle diseases

January 12, 2016 | Categories: Announcements | Tagged: , , , , ,

Congratulations to ISCRM’s Casey Childers and Hannele Ruohola-Baker who are contributing authors of a new book entitled Regenerative Medicine for Muscle Diseases. The book, edited by Casey Childers, delves into […] Read More

People sitting at outdoor tables and benches between two modern glass buildings on a sunny day, with string lights hanging above and greenery along the walkway.

ISCRM Faculty Member featured in The Scientist

December 1, 2015 | Categories: Announcements | Tagged: , , ,

The work of ISCRM faculty member, Casey Childers, on a gene therapy in children with a rare and fatal muscle weakness disorder called X-linked myotubular myopathy was highlighted in a Dec. 1, […] Read More

Faculty headshot of Martin K. Childers, PhD

Gene therapy leads to robust improvements in animal model of fatal muscle disease

January 22, 2014 | Categories: Research | Tagged: , ,

January 22, 2014 Preclinical studies show that gene therapy can improve muscle strength in small- and large-animal models of a fatal congenital childhood disease know as X-linked myotubular myopathy. The […] Read More