Head shot of Alec Smith

Developing a Neuromuscular Modeling System

October 6, 2022 | Categories: Award, Core Faculty | Tagged: , , , , ,

An NIH R03 grant and a UW Royalty Research Fund grant will allow ISCRM researchers and their partners to develop a modeling system that integrates neurons and skeletal muscle tissue. Read More

Modeling a Muscle Disease in 3D

August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized | Tagged: , ,

A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More

Early Stage Investigator Award for Alec Smith

January 8, 2021 | Categories: Announcements, Award | Tagged: , , , ,

Alec Smith finds the mentors to support his growth, opportunities to master the art of differentiating stem cells into neuronal and skeletal muscle, and critical funding to propel his path to independence. Read More

ISCRM Researchers to Play Pivotal Roles on NIH-Funded Collaboration with Stanford

July 10, 2019 | Categories: Announcements, Award, Core Faculty | Tagged: , , , , , ,

Over the last decade, human induced pluripotent stem cells (iPSCs) have become powerful tools of discovery for scientists around the world. Read More

Favorable interim results reported in stem-cell therapy trial

January 8, 2018 | Categories: Research | Tagged: , , ,

A therapy developed at UW shows promise in its first test in young boys who have an inherited deadly muscle disease. Favorable interim results have been announced in a small clinical trial of a stem-cell therapy to treat patients with a rare, deadly disease called myotubular myopathy. Read More

Transfer of the MTM1 gene into the weakened muscle tissue of dogs affected by myotubular myopathy restores muscle strength. The disease arises from a genetic mutation that disrupts the production of a protein needed for muscle function.

Gene therapy treats muscle-wasting disease in dogs

February 15, 2017 | Categories: Research | Tagged: , , ,

Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease. UW Medicine Institute for Stem Cell […] Read More

Xuan Guan

Disease-in-a-dish model to improve treatments

August 4, 2016 | Categories: Research | Tagged: , , ,

Scientists’ ability to guide cell growth drives one vision of healthcare’s future Say you’re sick. You head to your doctor and discuss personal details about your body. The doc thoughtfully […] Read More