Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart
May 2, 2024 | Categories: Research, Uncategorized |An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More
Developing a Neuromuscular Modeling System
October 6, 2022 | Categories: Award, Core Faculty |An NIH R03 grant and a UW Royalty Research Fund grant will allow ISCRM researchers and their partners to develop a modeling system that integrates neurons and skeletal muscle tissue. Read More
Modeling a Muscle Disease in 3D
August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized |A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More
NIH Funds Collaborative Effort to Pinpoint the Origins of Duchenne Muscular Dystrophy
February 18, 2021 | Categories: Award, Core Faculty, Research |
Early Stage Investigator Award for Alec Smith
January 8, 2021 | Categories: Announcements, Award |Alec Smith finds the mentors to support his growth, opportunities to master the art of differentiating stem cells into neuronal and skeletal muscle, and critical funding to propel his path to independence. Read More
New Insights from Mack Lab on Mechanisms of Gene Therapy for X-Linked Myotubular Myopathy
January 27, 2020 | Categories: Research |
ISCRM Researchers to Play Pivotal Roles on NIH-Funded Collaboration with Stanford
July 10, 2019 | Categories: Announcements, Award, Core Faculty |Over the last decade, human induced pluripotent stem cells (iPSCs) have become powerful tools of discovery for scientists around the world. Read More
Favorable interim results reported in stem-cell therapy trial
January 8, 2018 | Categories: Research |A therapy developed at UW shows promise in its first test in young boys who have an inherited deadly muscle disease. Favorable interim results have been announced in a small clinical trial of a stem-cell therapy to treat patients with a rare, deadly disease called myotubular myopathy. Read More
Gene therapy treats muscle-wasting disease in dogs
February 15, 2017 | Categories: Research |Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease. UW Medicine Institute for Stem Cell […] Read More
Disease-in-a-dish model to improve treatments
August 4, 2016 | Categories: Research |Scientists’ ability to guide cell growth drives one vision of healthcare’s future Say you’re sick. You head to your doctor and discuss personal details about your body. The doc thoughtfully […] Read More