Aided by Stem Cells, ISCRM Researchers Identify a Suspect in the Case of Infertility

February 7, 2019 | Categories: Core Faculty, Research | Tagged: ,

February 7, 2019 Of all the mysteries surrounding the beginning of human life, one question has drawn particular interest from researchers at the Institute for Stem Cell and Regenerative Medicine […] Read More

A colony of human embryonic stem cells

Move over Gucci; researchers create designer stem cells

September 1, 2017 | Categories: Research | Tagged: , , ,

UW Medicine researchers recently lead a successful effort to create “designer” stem cells that might lead to advances in cancer and aging, they say. In a paper published in the journal PNAS, the scientists showed for the first time that a computer-generated protein can be inserted into stem cells to change their epigenetic memory, whose role is to ensure that a cell’s DNA sequence remains intact as it divides. Read More

Deepkiran Singh

Stem cell research gets undergrads out of classroom

March 23, 2016 | Categories: Research | Tagged: , ,

Students help conduct intensive, real-world research at UW Medicine lab UW undergraduate Randy Lu grasps a pair of tweezers in each hand. His fingers make imperceptible movements as he dissects […] Read More

New book published on regenerative medicine for degenerative muscle diseases

January 12, 2016 | Categories: Announcements | Tagged: , , , , ,

Congratulations to ISCRM’s Casey Childers and Hannele Ruohola-Baker who are contributing authors of a new book entitled Regenerative Medicine for Muscle Diseases. The book, edited by Casey Childers, delves into […] Read More

Drs. Ruohola-Baker

Changes in metabolites can regulate earliest stages of development

November 16, 2015 | Categories: Research | Tagged: , , ,

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life. Metabolites are simple compounds generated during life-sustaining chemical activities in cells. […] Read More

Kavitha T. Kuppusamy led a study of a molecular switch that promotes heart cell maturation.

Molecular switch matures heart cells derived from stem cells

May 12, 2015 | Categories: Research | Tagged: , , ,

Discovery may prove a major advance in the development of stem cell treatments for heart disease A molecular switch that seems to be essential  for embryonic heart cells to grow […] Read More

At a University of Washington stem cell research lab

Dying cells can protect their stem cells from destruction

May 11, 2015 | Categories: Research | Tagged: , ,

An SOS signal from dying daughter cells allows their mother stem cells to protect themselves from radiation and chemotherapy damage Cells dying as the result of radiation exposure or chemotherapy […] Read More

Julie Mathieu (left)

Proteins that control energy use necessary to form stem cells

March 21, 2014 | Categories: Research | Tagged: , , ,

Findings advance efforts to reprogram mature cells for organ repair Two proteins that control how cells break down glucose play a key role in forming human stem cells, University of […] Read More

Laboratory fruit flies are used for quick screening of candidate drug treatments for Duchenne muscular dystrophy.

Burnt sugar-derivative reduces muscle wasting in fly and mouse models of muscular dystrophy

August 1, 2013 | Categories: Research | Tagged: , , , ,

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne muscular dystrophy. The findings are published Thursday (Aug. […] Read More

A colony of human embryonic stem cells.

Embryonic stem cells shift metabolism in a cancer-like way upon implanting in the uterus

March 23, 2012 | Categories: Research | Tagged: ,

March 23, 2012 Shortly after a mouse embryo starts to form, some of its stem cells undergo a dramatic metabolic shift to enter the next stage of development, Seattle researchers […] Read More