Freedman Lab Discovers Promising New Therapeutic for PKD in Tailor-Made Organoids
April 4, 2024 | Categories: Core Faculty, Research |In a new study published in Cell Stem Cell, the Freedman Lab shows that a drug known to be safe in humans inhibits the growth of cysts in gene-edited organoids with polycystic kidney disease. Read More
Mini-kidney organoids reveal renal disease secrets
October 2, 2017 | Categories: Research |Kidney organoids are revealing both the factors that influence the formation of kidney cysts, as well as how the disease progresses. The organoids are grown in labware from human stem cells. Polycystic kidney disease affects 12 million people. Until recently, scientists have been unable to recreate the progression of this human disease in a laboratory setting. Read More
New portal vividly reveals the diversity of cell structures
April 5, 2017 | Categories: Announcements |Textbook diagrams of cells show a cursory membrane, nucleus and mitochondria. They have never adequately conveyed cells’ variation and complexity. Seattle’s Allen Institute for Cell Science has unveiled an online portal with stunning […] Read More
Mini-kidney organoids re-create disease in lab dishes
October 23, 2015 | Categories: Research |Stem-cell biology and gene editing advances offer hope for kidney regeneration, drug discovery Mini-kidney organoids that re-create human kidney disease have now been grown in laboratory petri dishes. The achievement, […] Read More