FDA Approves Gene Therapy with ISCRM Origins

July 5, 2023 | Categories: Core Faculty, Research | Tagged: , , ,

The FDA has approved a first-ever gene therapy for Duchenne muscular dystrophy based in part on technology developed by UW Medicine/ISCRM Researchers Read More about FDA Approves Gene Therapy with ISCRM Origins

Gene Therapy Cassettes Improved for Muscular Dystrophy

February 1, 2019 | Categories: Research | Tagged: , , ,

February 1, 2019 Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance.  The cassettes, which carry the therapy into muscle cells, contain newer versions […] Read More about Gene Therapy Cassettes Improved for Muscular Dystrophy

Transfer of the MTM1 gene into the weakened muscle tissue of dogs affected by myotubular myopathy restores muscle strength. The disease arises from a genetic mutation that disrupts the production of a protein needed for muscle function.

Gene therapy treats muscle-wasting disease in dogs

February 15, 2017 | Categories: Research | Tagged: , , ,

Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease. UW Medicine Institute for Stem Cell […] Read More about Gene therapy treats muscle-wasting disease in dogs

Dr. Daniel Miller studies the molecular basis of muscle disorders in his lab at UW Medicine South Lake Union.

Mutations in genes that modify DNA packaging result in form of muscular dystrophy

November 19, 2012 | Categories: Research | Tagged: , , ,

November 19, 2012 A recent finding by medical geneticists sheds new light on how facioscapulohumeral muscular dystrophy develops and how it might be treated. More commonly known as FSHD, the […] Read More about Mutations in genes that modify DNA packaging result in form of muscular dystrophy