Helper or Culprit: Re-Examining the Role of Fibroblasts in Dilated Cardiomyopathy
September 11, 2025 | Categories: Core Faculty, Research, Uncategorized |In a paper published in Science, a multidisciplinary ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring. Read More
How Small Molecules Have a Big Impact on the Heart
October 23, 2024 | Categories: Core Faculty, Research |Researchers at UW and UCSD use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. Read More
Why Tiny Changes in Protein Structure Can Lead to Big Problems for the Heart
May 2, 2024 | Categories: Research, Uncategorized |An NIH-funded collaboration involving ISCRM researchers has published a study describing how complementary areas of expertise produced new insights about hypertrophic cardiomyopathy at the protein, cell, and tissue levels. Read More
WRF Fellowships for Two ISCRM Undergraduate Researchers
November 7, 2022 | Categories: Award, Core Faculty, Heart Regeneration |Undergraduate student researchers Dessirée Ortaç and Eesha Murali have received Washington Research Foundation Fellowships that will support their time in the lab through the end of the 2023 school year. Read More
Early Stage Investigator Award for Alec Smith
January 8, 2021 | Categories: Announcements, Award |Alec Smith finds the mentors to support his growth, opportunities to master the art of differentiating stem cells into neuronal and skeletal muscle, and critical funding to propel his path to independence. Read More
ISCRM Researchers to Play Pivotal Roles on NIH-Funded Collaboration with Stanford
July 10, 2019 | Categories: Announcements, Award, Core Faculty |Over the last decade, human induced pluripotent stem cells (iPSCs) have become powerful tools of discovery for scientists around the world. Read More
New Findings About dATP-Enhanced Heart Contractions Published in PNAS
May 21, 2019 | Categories: Core Faculty, Research |Heart failure is a widespread chronic condition that directly impacts nearly six million Americans, contributes to almost one in ten deaths in the United States, and drains an estimated $30 billion annually from our national economy. Read More
Gene therapy may aid failing hearts
March 26, 2013 | Categories: Research |March 26, 2013 The potential of gene therapy to boost heart muscle function was explored in a recent University of Washington animal study. The findings suggest that it might be […] Read More