Helper or Culprit: Re-Examining the Role of Fibroblasts in Dilated Cardiomyopathy
September 11, 2025 | Categories: Core Faculty, Research, Uncategorized |In a paper published in Science, a multidisciplinary ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring. Read More
User-Friendly 3D-Printed Device Will Allow Researchers to Model Human Tissue With Increased Control and Complexity
April 30, 2025 | Categories: Core Faculty, Research, Uncategorized |The device known as STOMP, developed by researchers from the Sniadecki and Theberge Labs, is small enough to fit on a human fingertip and is compatible with existing tissue engineering technology. Read More
Modeling the Periodontal Ligament in 3D
October 22, 2024 | Categories: Core Faculty, Research |A new 3D modeling tool developed by the Sniadecki Lab and Dr. Tracy Popwics in the School of Dentistry could lead to regenerative therapies for periodontal diseases. Read More
Meet the 2024 Tietze Award Winners
May 24, 2024 | Categories: Award, Core Faculty |ISCRM Associate Director Nate Sniadecki, PhD, Professor of Mechanical Engineering and Hichem Tasfaout, PhD, Acting Assistant Professor, Neurology have received prestigious awards from the John H. Tietze Foundation Trust that will help fuel promising research underway in their labs. Read More
Developing a Neuromuscular Modeling System
October 6, 2022 | Categories: Award, Core Faculty |An NIH R03 grant and a UW Royalty Research Fund grant will allow ISCRM researchers and their partners to develop a modeling system that integrates neurons and skeletal muscle tissue. Read More
Modeling a Muscle Disease in 3D
August 17, 2022 | Categories: Award, Core Faculty, Research, Uncategorized |A team of investigators led by ISCRM faculty members David Mack, PhD and Nate Sniadecki, PhD have shown that is possible to recreate DMD with much more complexity in a 3D model of engineered heart tissue. Read More
ISCRM Researchers Use Rainbow Reporters to Examine Proliferation of Engrafted Heart Cells
April 19, 2021 | Categories: Core Faculty, Heart Regeneration, Research, Uncategorized |ISCRM investigators use rainbow cell technology to demonstrate that injected heart cells proliferate, a finding that could help researchers enhance the efficacy of cell therapy for heart disease and other conditions. Read More
Early Stage Investigator Award for Alec Smith
January 8, 2021 | Categories: Announcements, Award |Alec Smith finds the mentors to support his growth, opportunities to master the art of differentiating stem cells into neuronal and skeletal muscle, and critical funding to propel his path to independence. Read More
